ArticleCureus2026
Incidence or Coincidence: Subaortic Membrane, Bicuspid Aortic Valve, and Aortic Root Dilatation in a Patient Presenting With Stroke.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation and is frequently associated with progressive aortopathy. Subaortic membrane, a discrete form of left ventricular outflow tract (LVOT) obstruction, is uncommon in adults and rarely coexists with BAV outside of complex congenital syndromes. The simultaneous presence of BAV, aortic root dilation, and a subaortic membrane represents an unusual anatomical constellation with important diagnostic and clinical implications. We present the case of a 49-year-old man with no known medical history who developed sudden, painless monocular vision loss and was diagnosed with left central retinal artery occlusion (CRAO). Neurovascular imaging revealed mild carotid atherosclerosis and incidental ascending aortic dilation. Transthoracic echocardiography (TTE) demonstrated a probable BAV, left atrial enlargement, and a suspected subaortic membrane with elevated LVOT gradients. Transesophageal echocardiography confirmed BAV morphology, mild aortic stenosis, and aortic root dilation measuring 4.2 cm, along with severe atherosclerotic plaque in the aortic arch, suggesting an embolic source. This case highlights the importance of comprehensive cardiac evaluation in patients with unexplained embolic events and expands the spectrum of structural abnormalities associated with BAV. Recognition of this rare triad is important for appropriate surveillance, risk stratification, and multidisciplinary management.
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