Evidence map›Paper›PMID 42005165›Full record

ArticleCureus2026

Early Multivessel Stent Thrombosis Causing Rapid Progression From Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) to ST-Segment Elevation Myocardial Infarction (STEMI) Requiring Mechanical Circulatory Support.

Mafaz Mansoor, Asma Yasin, Patrick Joseph, Roberta Baah-Sackey

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mafaz MansoorInternal Medicine, South Georgia Medical Center, Valdosta, USA.
Asma YasinInternal Medicine, South Georgia Medical Center, Valdosta, USA.
Patrick JosephInternal Medicine, South Georgia Medical Center, Valdosta, USA.
Roberta Baah-SackeyInternal Medicine, South Georgia Medical Center, Valdosta, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early stent thrombosis is an uncommon but life-threatening complication of percutaneous coronary intervention (PCI), associated with high mortality despite adherence to dual antiplatelet therapy (DAPT). Early stent thrombosis is a rare but serious complication of percutaneous coronary intervention that is often associated with significant morbidity and mortality. Multifactorial contributors, including diabetes mellitus and reduced left ventricular ejection fraction, significantly increase the risk. We present the case of a 50-year-old African American male with no prior medical history, presenting with persistent chest pain, nausea, vomiting, and diaphoresis. Initial workup revealed elevated troponins, and coronary angiography identified critical stenoses in the left anterior descending (LAD) and obtuse marginal (OM) arteries, which were treated with PCI with drug-eluting stents followed by DAPT. Further investigation revealed new-onset heart failure, diabetes, and hypercholesterolemia, prompting initiation of guideline-directed medical therapy (GDMT), insulin, and atorvastatin, respectively. The patient was discharged but returned within 24 hours with the new onset of chest pain. Emergency coronary angiography demonstrated occlusion of the proximal LAD at the stented segment as well as thrombotic occlusion involving the circumflex/OM stent, consistent with early stent thrombosis. Intravascular ultrasound (IVUS) performed during the repeat intervention demonstrated a relatively large reference vessel diameter of approximately 4.5 mm with areas of suboptimal stent expansion that may have contributed to thrombus formation. IVUS-guided repeat PCI was performed with high-pressure balloon post-dilation and additional stent optimization to restore thrombolysis in myocardial infarction grade 3 (TIMI-3) flow. Due to significant hemodynamic compromise with elevated left ventricular end-diastolic pressure (LVEDP) of 40 mmHg and hypoxia requiring non-invasive ventilatory support, mechanical circulatory support with an Impella CP

Indexed as

drug-eluting stentsearly stent thrombosisintravascular ultrasound (ivus)mechanical circulatory supportmultivessel thrombosispercutaneous coronary intervention (pci)

Identifiers

PMID42005165
PMCPMC13084941

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.