Evidence map›Paper›PMID 42004906›Full record

ArticleEuropean heart journal open2026

Effect of high-intensity interval training on peak oxygen uptake, quality of life, and ventricular arrhythmias in patients with an implantable cardioverter defibrillator: a randomized controlled trial.

Mathias Nyman, Ole Christian Mjølstad, Ane Cecilie Dale, Brage Høyem Amundsen, Ole Rossvoll, Ulrik Wisløff, Jan Pål Loennechen

Abstract read
In one paragraph

Article in European heart journal open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mathias NymanClinic of Cardiology, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006 Trondheim, Norway.ORCID https://orcid.org/0000-0001-9618-5107
Ole Christian MjølstadClinic of Cardiology, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006 Trondheim, Norway.ORCID https://orcid.org/0000-0002-7836-4838
Ane Cecilie DaleClinic of Cardiology, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006 Trondheim, Norway.
Brage Høyem AmundsenClinic of Cardiology, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006 Trondheim, Norway.ORCID https://orcid.org/0000-0001-7914-7395
Ole RossvollClinic of Cardiology, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006 Trondheim, Norway.
Ulrik WisløffDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Postboks 8905, 7491 Trondheim, Norway.ORCID https://orcid.org/0000-0002-7211-3587
Jan Pål LoennechenClinic of Cardiology, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006 Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Exercise is effective in preventing and treating cardiovascular disease. High-intensity interval training (HIIT) has shown promising effects on cardiorespiratory fitness and quality of life (QoL). However, evidence of risks and beneficial effects of HIIT in patients at high risk of ventricular arrhythmias (VA) is limited. This study evaluated the effects of HIIT on peak oxygen uptake (VO Methods and results: Fifty-six ICD patients with coronary artery disease (CAD) or non-ischaemic dilated cardiomyopathy (DCM) were randomized to a 12-week supervised HIIT programme with intervals at 85-95% of maximum heart rate, or to usual activity (control). Primary outcomes were changes in VO Conclusion: In ICD patients with CAD or non-ischaemic DCM, a supervised 12-week HIIT programme significantly improved exercise capacity and QoL. However, its overall impact on VA remains inconclusive, and the risk of exercise-induced arrhythmias remains a concern.

Indexed as

High-intensity interval trainingICDQuality of lifeVentricular arrhythmiaVO2peak

Identifiers

PMID42004906
PMCPMC13089605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.