ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2026
KaiWei JianPI Ointment Downregulates Fcgbp and Modulates HMGB1/TLR4 Signaling to Combat Ferroptosis in
Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- KaiWei JianPI Ointment Downregulates Fcgbp and Modulates HMGB1/TLR4 Signaling to Combat Ferroptosis inThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026Article
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Authors and funding
8 authors.
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Abstract
Objective: This study aimed to explore the therapeutic mechanisms of KaiWei JianPI Ointment in treating Methods: We used a combination of network pharmacology, molecular docking, transcriptome sequencing, and molecular biology in this study. Active components of the KaiWei JianPI Ointments were identified using the Traditional Chinese Medicine Systems Pharmacology database. Post-treatment transcriptomic changes in rat gastric tissues were analyzed to identify differentially expressed genes. Results: Network analysis identified 152 active components targeting key proteins involved in immune responses and cellular signaling. Transcriptome sequencing revealed 76 differentially expressed genes linked to immune response pathways. Additionally, treatment with the KaiWei JianPI Ointment resulted in decreased levels of Fe Conclusions: KaiWei JianPI Ointment shows potential as a novel therapeutic strategy against
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