Evidence map›Paper›PMID 42004873›Full record

ArticleClinical case reports2026

Life-Threatening Acute Tumor Lysis Syndrome With Multiorgan Failure Following First Cycle of Bendamustine-Rituximab in Chronic Lymphocytic Leukemia: A Case Report and Brief Review.

Malegna Temesgen Garuma, Kebede H Begna, Tesfaye Belete Amare, Mengisteab Kassahun Desta, Derebe Shashigo Leilago, Humud Mohammed Ahmed

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In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Malegna Temesgen GarumaDepartment of Internal Medicine St. Paul's Hospital Millennium Medical College (SPHMMC) Addis Ababa Ethiopia.ORCID https://orcid.org/0009-0005-4425-1375
Kebede H BegnaHematology-Oncology Unit, Department of Internal Medicine SPHMMC Addis Ababa Ethiopia.
Tesfaye Belete AmareDepartment of Internal Medicine St. Paul's Hospital Millennium Medical College (SPHMMC) Addis Ababa Ethiopia.
Mengisteab Kassahun DestaDepartment of Internal Medicine St. Paul's Hospital Millennium Medical College (SPHMMC) Addis Ababa Ethiopia.
Derebe Shashigo LeilagoDepartment of Internal Medicine St. Paul's Hospital Millennium Medical College (SPHMMC) Addis Ababa Ethiopia.
Humud Mohammed AhmedDepartment of Internal Medicine St. Paul's Hospital Millennium Medical College (SPHMMC) Addis Ababa Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic lymphocytic leukemia is not uniformly low risk for tumor lysis syndrome. This case shows that first-cycle bendamustine-rituximab in patients with high disease burden can precipitate severe TLS with acute kidney injury and multiorgan failure. Individualized prophylaxis, patient education, and close monitoring during early therapy are essential.

Indexed as

acute kidney injuryacute tumor lysis syndromeBendamustine–rituximabchronic lymphocytic leukemiahematologic emergencymultiorgan failure

Identifiers

PMID42004873
PMCPMC13083219

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.