Evidence map›Paper›PMID 42004834›Full record

ReviewEuropean urology open science2026

Effects of Nonpharmacological and Nonsurgical Intervention for Lower Urinary Tract Symptoms in Parkinson's Disease: A Systematic Review and Meta-analysis.

Hiroyuki Ohtsuka, Mifuka Ouchi, Tomoko Otsuka, Takeya Kitta, Daisuke Yoneoka, Ryuji Sakakibara

Abstract readReview
In one paragraph

Review in European urology open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroyuki OhtsukaGraduate School of Health Sciences, Showa University, Kanagawa, Japan.
Mifuka OuchiDepartment of Renal and Genitourinary Surgery, Graduate School of Medicine, Hokkaido University, Hokkaido, Japan.
Tomoko OtsukaDepartment of Nursing, Faculty of Healthcare Sciences, Chiba Prefectural University of Health Sciences, Chiba, Japan.
Takeya KittaDepartment of Renal and Urologic Surgery, Asahikawa Medical University, Hokkaido, Japan.
Daisuke YoneokaCenter for Surveillance, Immunization, and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo, Japan.
Ryuji SakakibaraNeurology Clinic Tsudanuma and Dowakai Chiba Hospital, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Lower urinary tract symptoms (LUTS) are common in Parkinson's disease (PD) and reduce quality of life. We assessed whether nonpharmacological and nonsurgical (NPNS) interventions improve PD-related LUTS. Methods: We searched PubMed, CENTRAL, PEDro, and CINAHL from inception to November 28, 2025, and screened reference lists. Randomized controlled trials (RCTs) and nonrandomized studies in adults with PD comparing NPNS interventions with no intervention, sham/placebo, or usual care were eligible. Primary outcomes were 24-h bladder-diary episodes (voids, urgency, incontinence). Secondary outcomes were validated symptom, bother, and urinary-related quality-of-life (QOL) scales. Random-effects meta-analyses used postintervention values. Risk of bias (RoB) was assessed with Cochrane RoB 2/RoB Assessment Tool for Non-randomized Studies, and certainty with the Grading of Recommendations, Assessment, Development and Evaluations approach. Key findings and limitations: Conclusions and clinical implications: NPNS interventions may improve some LUTS outcomes in PD, with the most consistent signal for urinary incontinence. More adequately powered trials enrolling patients with confirmed LUTS and using standardized LUTS-specific outcomes, follow-up, and comparator definitions are needed.

Indexed as

Lower urinary tract symptomsMeta-analysisNon-pharmacological and non-surgical interventionParkinson’s diseaseSystematic review

Identifiers

PMID42004834
PMCPMC13091170

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.