ArticleIEEE nanotechnology magazine2026
Smart Ultrasound-Responsive Nanoparticles for Drug Delivery.
Article in IEEE nanotechnology magazine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Drug delivery can be improved by incorporating the therapeutic molecules inside nano-sized carriers. This can enable controlled release of the drugs at the site of interest, thus minimizing off-target effects. Recent advances in nanotechnology have led to the development of "smart" nanoparticles, which can release their cargo in response to an external stimulus. Ultrasound is a promising external stimulus, because it is able to safely provide mechanical energy in a tightly focused region deep in soft tissue. In this region, the ultrasound provides pressure changes, heating, and/or shear forces that can facilitate drug release from the nanoparticles. In this review, we highlight recent advances in smart nanoparticles and describe how ultrasound could be used to achieve real-time on-demand drug delivery in situ. We also identify promising areas of future research that could lead to impactful drug delivery strategies.
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