ReviewVeterinary evidence
Gastric dilatation volvulus in dogs: utility of lactate as a predictor of survival.
Review in Veterinary evidence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PICO question In dogs presenting with gastric dilatation volvulus, is an admission or pre-operative lactate level a reliable predictor of survival to discharge? Clinical bottom line Category of research question Prognosis The number and type of study designs reviewed 15 studies (12 retrospective and 3 prospective) were critically appraised Strength of evidence Moderate Outcomes reported At a population level, lower blood lactate concentration, or lactate concentration that decreases following fluid resuscitation, are associated with a better prognosis. At a population level, higher blood lactate concentration, or lactate concentration that fails to decrease following fluid resuscitation, is associated with a worse prognosis. However, the lower sensitivity across studies means that a high lactate, or one that does not decrease following fluid therapy, should be interpreted more cautiously than a low lactate; i.e., low lactate predicts survival better than high lactate predicts non-survival. In all studies, there was a significant overlap in individual blood lactate concentration between survivors and non-survivors Conclusion Blood lactate level should only be used to help guide broad, cautiously worded conversations with owners. It should not be used to give a prognosis for individual patients. The overlap between survivors and non-survivors, and the high overall survival rate, suggest that exploratory laparotomy should be advised irrespective of the blood lactate level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.