Evidence map›Paper›PMID 42004629›Full record

ArticleCardiovascular endocrinology & metabolism2026

Evaluating the cardio-protective effects of

Bongiwe Khumalo, Angezwa Siboto, Akinjide Moses Akinnuga, Ntethelelo Sibiya, Andile Khathi, Phikelelani Siphosethu Ngubane

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Article in Cardiovascular endocrinology & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bongiwe KhumaloDepartment of Physiology, School of Laboratory Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban.
Angezwa SibotoDepartment of Human Physiology, Faculty of Science, Nelson Mandela University, Gqeberha.
Akinjide Moses AkinnugaDepartment of Physiology, School of Laboratory Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban.
Ntethelelo SibiyaPharmacology Division, Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa.
Andile KhathiDepartment of Physiology, School of Laboratory Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban.
Phikelelani Siphosethu NgubaneDepartment of Physiology, School of Laboratory Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular disease (CVD) is the predominant cause of morbidity and mortality among patients with type 1 or type 2 diabetes. The association between hyperglycemia and intracellular metabolic changes can result in oxidative stress, low-grade inflammation, and endothelial dysfunction. The management of hyperglycemia and prediabetes-associated vascular complications rely on pharmacotherapy and lifestyle intervention strategies. Research investigated the cardio-protective effects of Materials and methods: Prediabetes was induced using a laboratory established protocol in male Sprague Dawley rats. Thereafter, Results: Conclusion:

Indexed as

cardiovascular complicationsdietary interventionMomordica balsaminaprediabetes

Identifiers

PMID42004629
PMCPMC13090081

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.