ArticleAIMS neuroscience2026
Developmental and lifelong exposure to mercury chloride exacerbates cognitive and motor decline in aged mice.
Article in AIMS neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aging is a multifactorial biological process characterized by the progressive decline of cellular, tissue, and organ functions, leading to increased vulnerability to neurodegenerative disorders. Among the proposed mechanisms, the oxidative stress theory of aging remains one of the most widely accepted, emphasizing the role of reactive oxygen species (ROS) accumulation, particularly in the central nervous system (CNS). Mercury is a persistent environmental pollutant known to induce oxidative damage, but its contribution to age-related neuronal decline remains poorly understood. Our aim of this study was to investigate whether chronic HgCl
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