ReviewBiochemistry and biophysics reports2026
A comprehensive review on structural, chemical, and functional perspectives of dietary polysaccharide-driven gut microbiota modulation: Mechanisms and challenges.
Review in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Natural Polysaccharide-Mediated Nano-Delivery Systems for Osteoporosis Therapy From a Gut-Bone Axis Regulatory Perspective.Advanced healthcare materials · 2026Review
- Endophytic bacteria and fungi as a source of polysaccharides: production and characterization techniques.Frontiers in microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polysaccharides in the diet have been increasingly recognized as major modulators of gut microbiota and multifunctional ingredients in food systems. Despite extensive research on various polysaccharides regarding their prebiotic activities, a comprehensive approach towards an integration of structural characteristics, chemical modifications, mechanistic degradation pathways, and food processing effects is still limited. This review aims to compile existing knowledge regarding the molecular characteristics of polysaccharides, including their monosaccharide composition, glycosidic linkages, branching, and molecular weight, in relation to their utilization by gut microbiota, production of short-chain fatty acids, and associated metabolic effects in the human body. Furthermore, this review will focus on carbohydrate-active enzymes and cross-feeding effects that play a major role in determining the biological activities of polysaccharides. The effects of food processing and food systems on polysaccharide functionality and utilization will also be considered. Despite promising therapeutic and nutritional potential, existing inconsistencies in research methods and a lack of standardized approaches in studying mechanistic effects are major hurdles in developing novel food systems that are targeted towards modulating gut microbiota.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.