Evidence map›Paper›PMID 42004440›Full record

ArticleEpilepsy & behavior reports2026

Surgical resection as salvage therapy for super-refractory status epilepticus: a report of two cases.

Jiangwei Ding, Chengbin Zhao, Dingge Cui, Wei Du, Hongliang Jiao

Abstract read
In one paragraph

Article in Epilepsy & behavior reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jiangwei DingDepartment of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Chengbin ZhaoDepartment of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Dingge CuiHenan Epilepsy Diagnosis and Treatment Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Wei DuDepartment of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Hongliang JiaoDepartment of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Super-refractory status epilepticus (SRSE) carries high mortality and morbidity when pharmacological treatments fail. We aimed to evaluate the efficacy of emergency surgical resection for terminating SRSE secondary to focal cortical dysplasia (FCD) and ganglioglioma (GG). Methods: We present two cases of SRSE caused by frontal lobe FCD and GG that were unresponsive to maximal medical therapy. Both patients underwent emergency resection of the epileptogenic zone after comprehensive presurgical evaluation. Results: In both cases, surgical intervention successfully terminated SRSE. Case 1, a 22-year-old female with left frontal FCD, achieved Engel Class IB outcome at 4 years and 5 months follow-up. Case 2, a 34-year-old female with right frontoparietal GG, remained seizure-free 4.5 months follow-up. No serious surgical complications occurred. Conclusion: Emergency epilepsy surgery may represent a life-saving therapeutic option for selected patients with SRSE and identifiable structural lesions. Our findings support the inclusion of surgical evaluation in SRSE treatment protocols when pharmacological interventions fail. Multimodal imaging and prompt surgical decision-making are crucial for successful outcomes.

Indexed as

Epilepsy surgeryFocal cortical dysplasiaRefractory status epilepticusStatus epilepticusSuper-refractory status epilepticus

Identifiers

PMID42004440
PMCPMC13091227

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.