Evidence map›Paper›PMID 42004363›Full record

ArticleACS omega2026

Protein Large Language Models Can Predict

Rafael Montilla, Letícia Dias Lima Jedlicka, Uilla Barcick, Murilo Salardani, Alison Felipe Alencar Chaves, Gloria Gallo, Marcela Guimarães, Camila Coelho, Larissa Slivka, André Zelanis and 1 more

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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rafael MontillaDepartment of Science and Technology, Biochemistry and Structural Biology Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
Letícia Dias Lima JedlickaDepartment of Science and Technology, Functional Proteomics Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
Uilla BarcickDepartment of Science and Technology, Functional Proteomics Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
Murilo SalardaniDepartment of Science and Technology, Functional Proteomics Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
Alison Felipe Alencar ChavesLaboratory of Applied Toxinology, Center of Toxins, Immune-Response and Cell Signaling (CeTICS), Instituto Butantan, São Paulo 05503-000, Brazil.ORCID https://orcid.org/0000-0001-6017-6671
Gloria GalloDepartment of Science and Technology, Biochemistry and Structural Biology Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
Marcela GuimarãesDepartment of Science and Technology, Biochemistry and Structural Biology Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
Camila CoelhoDepartment of Science and Technology, Biochemistry and Structural Biology Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.ORCID https://orcid.org/0000-0002-6904-8681
Larissa SlivkaDepartment of Science and Technology, Biochemistry and Structural Biology Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
André ZelanisDepartment of Science and Technology, Functional Proteomics Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.
Martin WürteleDepartment of Science and Technology, Biochemistry and Structural Biology Laboratory, Federal University of São Paulo - UNIFESP, São José dos Campos, São Paulo 12231-280, Brazil.ORCID https://orcid.org/0000-0001-8571-419X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral proteases are essential enzymes in many viral strains, playing a crucial role in the viral replication cycle. They are key targets for antiviral drug development and have significant implications for viral pathogenesis. To address the issue of

Identifiers

PMID42004363
PMCPMC13084463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.