Evidence map›Paper›PMID 42004359›Full record

ArticleACS omega2026

The Anticarcinogenicity Effects of Piperine and 4,5-Dihydroxypiperine in

Wellington S Aguiar, Isabelle V A Pires, Lívia M L Barros, Pedro M Almeida, José L S Sá, Benedito S Lima-Neto, Francielle A Martins

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wellington S AguiarGraduate Program in Chemistry, State University of Piauí, Teresina, 64002-150 Piauí, Brazil.
Isabelle V A PiresGenetics Laboratory, Center of Natural Sciences, State University of Piauí, Teresina, 64002-150 Piauí, Brazil.
Lívia M L BarrosGenetics Laboratory, Center of Natural Sciences, State University of Piauí, Teresina, 64002-150 Piauí, Brazil.
Pedro M AlmeidaGraduate Program in Chemistry, State University of Piauí, Teresina, 64002-150 Piauí, Brazil.
José L S SáGraduate Program in Chemistry, State University of Piauí, Teresina, 64002-150 Piauí, Brazil.
Benedito S Lima-NetoInstitute of Chemistry of São Carlos, University of São Paulo, São Carlos, 13560-970 SP, Brazil.ORCID https://orcid.org/0000-0003-1863-2439
Francielle A MartinsGraduate Program in Chemistry, State University of Piauí, Teresina, 64002-150 Piauí, Brazil.ORCID https://orcid.org/0000-0002-0113-8023

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asymmetric dihydroxylation of piperine (PIP) was investigated under various reaction conditions. Using AD-mix-α in the presence of methanesulfonamide, the reaction yield was approximately 51% at 25 °C, whereas the reactions with RuCl

Identifiers

PMID42004359
PMCPMC13084445

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.