Multianalytical and Theoretical Tendency for the Clarification of the Binding of Lansoprazole and Albumin Protein.

Murat Çelik, Cigdem Kanbes-Dindar, Ruqia Khan, Fazal Rehman, Gulsum Ece Meraki, Saharuddin Bin Mohamad, Ali Onur Asap, Fatih Inci, Bengi Uslu

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Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Murat ÇelikFaculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Ankara 06560, Turkiye.

Cigdem Kanbes-DindarFaculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Ankara 06560, Turkiye.ORCID https://orcid.org/0000-0002-3557-5029

Ruqia KhanDepartment of Chemistry, Quaid-I Azam University Islamabad, Islamabad 45320, Pakistan.

Fazal RehmanBiochemistry Program, Institute of Biological Sciences, Faculty of Science, University Malaya, Kuala Lumpur 50603, Malaysia.

Gulsum Ece MerakiFaculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Ankara 06560, Turkiye.ORCID https://orcid.org/0009-0005-1407-622X

Saharuddin Bin MohamadFaculty of Science, Bioinformatics Programme, Institute of Biological Sciences, University of Malaya, Kuala Lumpur 50603, Malaysia.

Ali Onur AsapUNAMNational Nanotechnology Research Center, Bilkent University, Ankara 06800, Turkiye.

Fatih InciUNAMNational Nanotechnology Research Center, Bilkent University, Ankara 06800, Turkiye.ORCID https://orcid.org/0000-0002-9918-5038

Bengi UsluFaculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Ankara 06560, Turkiye.ORCID https://orcid.org/0000-0002-7327-4913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the interaction between pharmaceutical agents and serum albumin is critical for assessing drug bioavailability, distribution, and pharmacokinetics. In this study, the binding mechanism of lansoprazole (LAN) to bovine serum albumin (BSA) was systematically investigated using spectroscopic, electrochemical, and computational approaches. Fluorescence quenching experiments showed that the interaction follows a dynamic quenching mechanism and a moderate affinity, revealing a binding constant of 1.25, 2.76, and 5.24 × 10

Identifiers

PMID42004332

DOI10.1021/acsomega.5c09146

PMCPMC13084387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.