Evidence map›Paper›PMID 42004193›Full record

ArticleCase reports in immunology2026

Adult Onset of Acute Disseminated Encephalomyelitis (ADEM) With Associated Myelin Oligodendrocyte Glycoprotein (MOG) Antibody.

Daniel Wilmot, Kaylee Sorrells, Sydnee Guthrie, Sapna Vyas, Mackenzie Lupov

Abstract read
In one paragraph

Article in Case reports in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel WilmotDepartment of Internal Medicine, Indiana University School of Medicine, Bloomington, Indiana, USA, indiana.edu.ORCID https://orcid.org/0009-0007-8443-391X
Kaylee SorrellsDepartment of Internal Medicine, Indiana University School of Medicine, Bloomington, Indiana, USA, indiana.edu.
Sydnee GuthrieDepartment of Internal Medicine, Indiana University School of Medicine, Bloomington, Indiana, USA, indiana.edu.
Sapna VyasDepartment of Internal Medicine, Indiana University School of Medicine, Bloomington, Indiana, USA, indiana.edu.
Mackenzie LupovDepartment of Internal Medicine, Indiana University School of Medicine, Bloomington, Indiana, USA, indiana.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ADEM is an inflammatory and demyelinating autoimmune disorder of the central nervous system (CNS). One recognized cause of ADEM is myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). MOGAD affects approximately one in 10,000 people worldwide and is more prevalent in children. Patients typically present with optic neuritis, ADEM, and transverse myelitis. Many patients will experience relapses of demyelinating attacks, and thus, both acute and maintenance therapies are typically used to manage the disease. This case considers an adult female who presented with neurological deficits as a result of MOG-associated ADEM. She had minimal response to traditional therapies but responded well to treatment with IV immunoglobulin (IVIG). This case report explores her clinical course as well as unique clinical significance and conclusions due to the nontraditional use of IVIG.

Identifiers

PMID42004193
PMCPMC13091007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.