Evidence map›Paper›PMID 42004188›Full record

ArticleWellcome open research2026

Adoption and use of the 7-1-7 target for timely outbreak detection, notification and early response in the human and animal sectors in humanitarian crisis-affected South Sudan: A mixed-methods study during 2025.

Joseph Daniel Wani Lako, Angelo Goup Thon, Agol Malak Kwai, Santino Ngong Garang, John Mabior Aguto, Santino Makuach, Santo Malek Deng, Harriet Akello Pasquale

Abstract read
In one paragraph

Article in Wellcome open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joseph Daniel Wani LakoDepartment of Biotechnology, University of Juba, Juba, Central Equatoria, South Sudan.ORCID https://orcid.org/0000-0001-7112-5060
Angelo Goup ThonDepartment of Health Security, SURGE, Capacity Development, and One Health, Ministry of Health, Juba, South Sudan.ORCID https://orcid.org/0000-0003-3697-8652
Agol Malak KwaiDirectorate of Veterinary Services, Ministry of Livestock and Fisheries, Juba, South Sudan.
Santino Ngong GarangDepartment of Health Security, SURGE, Capacity Development, and One Health, Ministry of Health, Juba, South Sudan.
John Mabior AgutoDepartment of Health Security, SURGE, Capacity Development, and One Health, Ministry of Health, Juba, South Sudan.
Santino MakuachDepartment of Health Security, SURGE, Capacity Development, and One Health, Ministry of Health, Juba, South Sudan.
Santo Malek DengDirectorate of International Health Coordination (IHC), Ministry of Health, Juba, South Sudan.
Harriet Akello PasqualeDirectorate of International Health Coordination (IHC), Ministry of Health, Juba, South Sudan.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: Globally, the 7-1-7 target (detect within 7 days, notify within 1 day, respond within 7 days) was introduced to improve outbreak response. South Sudan adopted the 7-1-7 framework in August 2023. This study aimed to describe the process and challenges of adopting the 7-1-7 framework, assess the performance of outbreaks in the animal and human sector against the 7-1-7 target, and explore the challenges for 7-1-7 adoption in humanitarian settings. Methods: This mixed-methods study comprised a checklist-based assessment of 7-1-7 adoption at national and subnational levels, extraction of dates and bottlenecks from the 7-1-7 consolidated spreadsheet for outbreaks that occurred before (2013-July 2023) and after (August 2023-July 2025) 7-1-7 adoption, and in-depth interviews and focus group discussions among key stakeholders to explore the challenges in 7-1-7 adoption. Results: 7-1-7 was successfully adopted at the national level and in four of ten states and three administrative areas, facilitated by strong leadership, and project funding and technical support from the 7-1-7 Alliance. Due to lack of funds, 7-1-7 was not adopted nation-wide. Data for applying the 7-1-7 framework was available in 9/25 (36%) and 9/9 (100%) outbreaks that occurred before and after adoption, respectively. None of the five outbreaks from the animal sector had complete data for assessing the target. Of 18 outbreaks assessed, 44% met all targets with 50%, 91% and 56% achieving detection, notification and response targets, respectively. Delayed health seeking, poor internet connectivity, and inadequate resources were bottlenecks for timely detection, notification, and response, respectively. Non-functional health facilities and competing priorities were major barriers to adopting the 7-1-7 framework in humanitarian settings. Conclusion: South Sudan successfully adopted 7-1-7 at the national-level. Sustainable funding is required to expand 7-1-7 to all states, including humanitarian settings, establish a surveillance information system for the animal sector and improve timely outbreak response.

Indexed as

bottleneckdisease notificationdisease outbreaksearly diagnosispandemic preparednessresource-limited settingsresponsevulnerable populations

Identifiers

PMID42004188
PMCPMC13090763

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.