Evidence map›Paper›PMID 42004046›Full record

ArticleRespirology case reports2026

Systemic AL (λ) Amyloidosis Discovered After Neoadjuvant Pembrolizumab-Based Chemoimmunotherapy for Resectable NSCLC: Case Report.

Weijie Ma, Dana M Ferrari-Light, Liang Lu

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Weijie MaDepartment of Pathology and Laboratory Medicine Dartmouth-Hitchcock Medical Center Lebanon New Hampshire USA.ORCID https://orcid.org/0000-0002-4434-1371
Dana M Ferrari-LightGeisel School of Medicine at Dartmouth Hanover New Hampshire USA.ORCID https://orcid.org/0000-0002-7658-5442
Liang LuDepartment of Pathology and Laboratory Medicine Dartmouth-Hitchcock Medical Center Lebanon New Hampshire USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic AL amyloidosis is rarely reported in temporal association with immune checkpoint inhibitor use. We report a 69-year-old man with resectable stage IIB right upper lobe lung adenocarcinoma who received neoadjuvant pembrolizumab, carboplatin, and pemetrexed followed by robotic-assisted lobectomy. Pathology showed a 4.6-cm treated tumour bed with residual invasive adenocarcinoma (50% viable), negative margins, and no nodal metastasis (0/9). Tumour profiling demonstrated a PD-L1 tumour proportion score of 100%, a high tumour mutational burden (18 mut/Mb), microsatellite stability, and variants in

Indexed as

AL amyloidosisimmune checkpoint inhibitorlung adenocarcinomaneoadjuvant immunotherapy

Identifiers

PMID42004046
PMCPMC13087107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.