ArticleOncology letters2026
Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report.
Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Solid tumors combined with eosinophilia are a rare clinical presentation. The present study reports a case of squamous carcinoma of the lung with peripheral blood eosinophilia that developed concurrent with a period of rapid deterioration, without any obvious clinical symptoms of eosinophilia, in a 25-year-old female patient. To the best of our knowledge, this is the first report in such a young patient. The current case favored the diagnosis of paraneoplastic eosinophilia after excluding multiple secondary and non-cancerous factors. However, the lack of bone marrow aspiration results to rule out leukemia posed a clinical diagnostic challenge. The application of glucocorticoids in combination with antineoplastic agents led to a marked decrease in peripheral blood eosinophils. The present case report emphasizes the importance of early recognition of the potential role of eosinophils in squamous lung cancer. The current report aims to provide a reference for the clinical management of similar cases.
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