ArticleJournal of the American Heart Association2026
Outcomes and Risk Factors for Postoperative Vasoplegia Following Implant of Left Ventricular Assist Devices.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPostoperative vasoplegia syndrome (PVS) following cardiac surgery has previously been associated with poor survival. This study aimed to investigate outcomes and predictors of PVS following left ventricular assist device implantation.
methodsThis was a retrospective study of 190 left ventricular assist device recipients at The Ohio State University. Primary outcomes included hospitalization duration, right-sided heart failure, and mortality. Risk factor evaluation included multivariate analysis of cardiovascular comorbidities and perioperative medication use. Patients were stratified into PVS (n=50, 26.3%) and non-PVS cohorts.
resultsOn univariate analysis, PVS was associated with male sex (94% versus 67%,
conclusionsPVS did not confer inferior outcomes after left ventricular assist device implantation but was associated with male sex and higher body mass index. Preoperative dobutamine was more commonly used in patients without PVS, warranting further investigation.
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