Evidence map›Paper›PMID 42003616›Full record

ArticlemBio2026

Utilization of a CRISPRi-based

Monique E Theriault, Andrew I Wong, Michael A DeJesus, Davide Pisu, Bom Nae Rin Lee, Greana Kirukubar, Shuqi Li, Joshua B Wallach, Dirk Schnappinger, Gabrielle Lê-Bury and 2 more

Erratum issuedAbstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Monique E TheriaultDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Andrew I WongLaboratory of Host-Pathogen Biology, The Rockefeller University, New York, New York, USA.
Michael A DeJesusLaboratory of Host-Pathogen Biology, The Rockefeller University, New York, New York, USA.
Davide PisuDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Bom Nae Rin LeeDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Greana KirukubarDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Shuqi LiLaboratory of Host-Pathogen Biology, The Rockefeller University, New York, New York, USA.
Joshua B WallachDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA.
Dirk SchnappingerDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-4445-7219
Gabrielle Lê-BuryDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-4650-5990
David G RussellDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-9748-750X
Jeremy M RockLaboratory of Host-Pathogen Biology, The Rockefeller University, New York, New York, USA.ORCID 0000-0002-9310-951X

Funding

Systems Biology CoreU19AI162598 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI DIETZE, REYNALDO · 2021 to 2025
$13.9M
Lung immune function in human TB infection and its perturbation by HIV-1.R01AI155319 · NIAID · CORNELL UNIVERSITY · PI MWANDUMBA, HENRY CHARLES, RUSSELL, DAVID G · 2020 to 2024
$3.3M
Bill and Melinda Gates Foundation INV-055894NIAID NIH HHS R01 AI155319NIAID NIH HHS U19 AI162598
6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

CRISPR-Cas SystemsGenes, EssentialMycobacterium tuberculosisAnimalsDisease Models, AnimalLungMacrophagesMiceMice, Inbred C57BLTuberculosisCRISPR genetic screengranulomamacrophageMycobacterium tuberculosis

Identifiers

PMID42003616
PMCPMC13170276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.