ArticleAntimicrobial agents and chemotherapy2026
Population pharmacokinetics and exposure-response analysis of levofloxacin in Chinese pediatric patients with severe refractory
Xingru Tao, Yuxue Zhou, Shasha Xu, Yanyan Su, Yu Tang, Shengnan Zhang, Zhao Chang, Feifan Xie, Meng Lv
Abstract read
In one paragraphArticle in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Xingru TaoDepartment of Pharmacy, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Yuxue ZhouDepartment of Pharmacy, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Shasha XuDepartment of Respiratory Medicine, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Yanyan SuDepartment of Respiratory Medicine, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Yu TangDepartment of Respiratory Medicine, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Shengnan ZhangDepartment of Pharmacy, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Zhao ChangDepartment of Pharmacy, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Feifan XieDivision of Biopharmaceutics and Pharmacokinetics, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.ORCID 0000-0002-9038-2676 Meng LvDepartment of Pharmacy, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.ORCID 0000-0003-3961-255X Funding
Medical Scientific and Technological Project in Henan Province LHGJ20230587Scientific and Technological Project in Henan Province 262102311034Zhengzhou Medical Research Project ZZYK2024088
6 · The paper itselfAbstract
Levofloxacin is recommended as an optional treatment for pediatric patients with severe refractory
Indexed as
Anti-Bacterial AgentsLevofloxacinMycoplasma pneumoniaePneumonia, MycoplasmaAdolescentArea Under CurveChildChild, PreschoolEast Asian PeopleFemaleHumansInfantMaleMicrobial Sensitivity TestsMonte Carlo MethodAnti-Bacterial AgentsLevofloxacinexposure-response analysislevofloxacinpediatric patientspopulation pharmacokineticssevere refractory Mycoplasma pneumoniae pneumonia
Identifiers
PMID42003577
PMCPMC13231918
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