Evidence map›Paper›PMID 42003426›Full record

ArticleAdvanced healthcare materials2026

Nanobody-Conjugated Theranostic Prodrug Targeting α

Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son and 4 more

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sanu KaranCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Hyunseung LeeCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Rema NaskarImmunology and Immunopharmacology Laboratory, College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
Mi Young ChoCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Hye Sun ParkCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Eun Hee HanCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Soumyadip HoreDepartment of Chemistry, Korea Advance Institute of Science and Technology, Daejeon, Republic of Korea.
Sun Hee ChoCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Truc Ngoc Kim LamCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Taewoong SonCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Tae Jung ParkCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.
Inkyu HwangImmunology and Immunopharmacology Laboratory, College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin, Austin, Texas, USA.ORCID https://orcid.org/0000-0002-9576-1325
Kwan Soo HongCenter For Target-to-Therapeutics Research, Korea Basic Science Institute, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0003-4342-5183

Funding

KEIT grant from the Korea government RS-2025-25462597Korea Basic Science Institute C523200National Research Council of Science & Technology (NST) grant from the Korea government GTL24022-000NIH HHS CA 068682
6 · The paper itself

Abstract

Theranostic prodrugs that integrate diagnostic and therapeutic functionalities represent a promising avenue for precision oncology. In this study, we report the rational design, synthesis, and preclinical evaluation of a nanobody-based α

Indexed as

Integrin alphaVbeta3NeoplasmsProdrugsSingle-Domain AntibodiesTheranostic NanomedicineAnimalsCell Line, TumorDoxorubicinFemaleHumansMiceMice, NudeXenograft Model Antitumor AssaysDoxorubicinIntegrin alphaVbeta3ProdrugsSingle-Domain Antibodiesnanobodynear‐infrared imagingprecision oncologytheranostic prodrugαvβ3 integrin

Identifiers

PMID42003426
PMCPMC13279852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.