ArticleCancer control : journal of the Moffitt Cancer Center
Clinical Characteristics and Cancer-Specific Survival of Adolescents and Young Adults With Pancreatic Neuroendocrine Tumors: A SEER-Based Study.
Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
IntroductionPancreatic neuroendocrine tumors (PanNETs) have shown an increasing incidence, yet population-based studies examining the clinical characteristics and cancer-specific survival (CSS) specifically in adolescents and young adults (AYA) (aged 13-39 years) remain scarce.MethodsThis population-based, retrospective cohort study identified all patients diagnosed with PanNETs through the Surveillance, Epidemiology, and End Results (SEER) database. Propensity score matching (PSM) was adopted to reduce selection bias. Kaplan-Meier analyses and Cox proportional hazards models were used to evaluate the impact of demographic and clinical variables on CSS. Temporal trends in incidence by age group were also assessed over the study period.ResultsA total of 4408 patients were included, with 338 in the AYA group and 4,070 in the older adult (OA) group (aged ≥ 40 years). Compared to the OA group, the AYA group had more female patients, earlier clinical staging, lower distant metastasis rates, and higher surgical treatment rates (
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