Evidence map›Paper›PMID 42002802›Full record

ArticleJournal of biophotonics2026

Therapeutic Effect of Photobiomodulation and Single Intratendinous Injection at the Lesion Site of Platelet-Rich Fibrin in Inducted Tendinopathy.

Caroline Hammerschmitt Wild, Pâmela Andressa Pauletto, Fransael Franklyn Araújo da Silva, Maria Eduarda Luckner, Gladson Ricardo Flor Bertolini

Abstract read
In one paragraph

Article in Journal of biophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caroline Hammerschmitt WildUniversidade Estadual Do Oeste Do Paraná - UNIOESTE - Cascavel, Cascavel, Brazil.
Pâmela Andressa PaulettoUniversidade Estadual Do Oeste Do Paraná - UNIOESTE - Cascavel, Cascavel, Brazil.
Fransael Franklyn Araújo da SilvaUniversidade Federal Do Paraná - UFPR - Palotina, Cascavel, Brazil.
Maria Eduarda LucknerUniversidade Estadual Do Oeste Do Paraná - UNIOESTE - Cascavel, Cascavel, Brazil.
Gladson Ricardo Flor BertoliniUniversidade Estadual Do Oeste Do Paraná - UNIOESTE - Cascavel, Cascavel, Brazil.ORCID 0000-0003-0565-2019

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
6 · The paper itself

Abstract

Tendinopathy is a multifactorial condition characterized by collagen disorganization, inflammation, and impaired tendon function. Photobiomodulation (PBM) and platelet-rich fibrin (PRF) have emerged as therapeutic approaches due to their regenerative potential, although their mechanisms during tendon healing remain unclear. This study compared the effects of PBM and PRF, alone or combined, on experimentally induced calcaneal tendinopathy in rats. A total of 75 animals were divided into five groups: control, injury, PRF, PBM, and PRF + PBM. Treatments began 48 h after injury. Functional performance, nociception, and histological features were evaluated up to 21 days. Combined PRF and PBM promoted superior early functional recovery, enhanced collagen synthesis, and increased angiogenesis, despite greater initial inflammation. PBM alone resulted in gradual recovery with better fiber organization, while PRF accelerated function but sustained inflammation. Combined therapy shows promise for tendon repair, supporting stage-specific treatment strategies.

Indexed as

Low-Level Light TherapyPlatelet-Rich FibrinTendinopathyTendonsAnimalsInjectionsMaleRatsfibrinphotobiomodulationphysiotherapyplateletstendon

Identifiers

PMID42002802
PMCPMC13092645

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.