Evidence map›Paper›PMID 42001565›Full record

ArticleClinics (Sao Paulo, Brazil)2026

Effects of vitamin D supplementation combined with resistance exercise on body composition and metabolic variables in older women: a randomized clinical trial.

Illana Patricia da Silva Queiroz, Angélica Castilho Alonso, Vanderlei Carneiro da Silva, Adriana Machado-Lima, Priscila Long Amorim Bichara Pipa, José Maria Soares-Junior, Edmund Chada Baracat, Júlia Maria D'Andréa Greve, Marta Ferreira Bastos, Guilherme Carlos Brech

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Illana Patricia da Silva QueirozGraduate Program in Aging Sciences, Universidade São Judas Tadeu, São Paulo, SP, Brazil.
Angélica Castilho AlonsoGraduate Program in Aging Sciences, Universidade São Judas Tadeu, São Paulo, SP, Brazil; Movement Study Laboratory, Institute of Orthopedics and Traumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
Vanderlei Carneiro da SilvaMovement Study Laboratory, Institute of Orthopedics and Traumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
Adriana Machado-LimaGraduate Program in Aging Sciences, Universidade São Judas Tadeu, São Paulo, SP, Brazil; Movement Study Laboratory, Institute of Orthopedics and Traumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
Priscila Long Amorim Bichara PipaGraduate Program in Aging Sciences, Universidade São Judas Tadeu, São Paulo, SP, Brazil.
José Maria Soares-JuniorDepartment of Obstetrics and Gynecology, Gynecology Discipline, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
Edmund Chada BaracatDepartment of Obstetrics and Gynecology, Gynecology Discipline, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
Júlia Maria D'Andréa GreveMovement Study Laboratory, Institute of Orthopedics and Traumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
Marta Ferreira BastosGraduate Program in Aging Sciences, Universidade São Judas Tadeu, São Paulo, SP, Brazil.
Guilherme Carlos BrechGraduate Program in Aging Sciences, Universidade São Judas Tadeu, São Paulo, SP, Brazil; Movement Study Laboratory, Institute of Orthopedics and Traumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil; Graduate Program in Physical Education, Universidade São Judas Tadeu, Brazil. Electronic address: guibrech@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAging has a significant impact on health, leading to changes in body composition and physical functionality in older adults.

objectiveGiven the relevance of this topic, the aim of this study was to analyze the effects of vitamin D supplementation combined with physical exercise over a 12-week period on body composition and metabolic profile in elderly women.

methodsThe study followed a clinical approach, employing a randomized, double-blind, placebo-controlled trial, in accordance with the guidelines established by the Consolidated Standards of Reporting Trials (CONSORT), conducted at the Movement Studies Laboratory in São Paulo, Brazil. Analyses were performed using an intention-to-treat approach with random effects regression models. The study sample consisted of 46 elderly individuals, divided into two groups with 23 participants each. The experimental group received vitamin D3 supplementation at a dose of 49,000 IU/week, while the placebo group received seven capsules of the same size, volume, and color, containing lactose but no vitamin D3.

resultsAfter analyzing the results, it was observed that the groups were homogeneous in terms of age (p = 0.7658) and BMI (p = 0.5904). The results showed differences in 25-OH vitamin D levels (p < 0.001) between the groups over time.

conclusionIn conclusion, vitamin D supplementation successfully increased serum levels but failed to provide additional benefits for muscle mass or metabolic markers compared to resistance training alone.

Indexed as

AgingBody compositionPhysical exerciseVitamin D supplementation

Identifiers

PMID42001565
PMCPMC13101711

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.