SynthesisMedicina oral, patologia oral y cirugia bucal2026
Influence of periodontal conditions on quality of life in patients with chronic kidney disease: A systematic review and meta-analysis.
Synthesis in Medicina oral, patologia oral y cirugia bucal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundChronic kidney disease (CKD) is associated with a higher occurrence of periodontitis, which may be linked to negative psychosocial and physical impacts on the lives of patients affected by both conditions. Therefore, the aim of this systematic review was to evaluate whether periodontal conditions influence OHRQoL in patients with CKD. MATERIALS AND
methodsElectronic searches were performed in five databases up to May 2025. Observational studies conducted in individuals with CKD that investigated the relationship between periodontal conditions through clinical examinations and OHRQoL, were included. Meta-analyses were performed to estimate the mean difference (MD) in OHRQoL, as well as the correlation.
resultsOut of the 2036 potentially eligible reports, 7 studies of patients with end-stage renal disease (ESRD) were included. Pooled estimates demonstrated that OHIP-14 scores are higher in individuals with ESRD compared to healthy controls. Impaired OHRQoL can be attributed to the higher prevalence of periodontitis in renal patients. Considering a score-response gradient, those with stage III/IV periodontitis had higher OHIP-14 scores compared to patients without periodontitis or with stage I/II periodontitis (MD:1.88; 95%CI: 0.67-3.09; p=0.002). Pooled estimates demonstrated a weak but significant positive correlation between periodontal probing depth (r=0.145; p=0.028) and plaque index (r=0.385; p<0.001) with OHIP-14 scores.
conclusionsSevere periodontitis, along with higher probing depth and plaque scores, negatively influences the OHRQoL of patients with ESRD. However, these relationships show a small magnitude.
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