ArticlePlant, cell & environment2026
A Water-Saving Drought Survival Phenotype in a Wheat TILLING Mutant Involves Survival-Biased Metabolic and Phosphorylation Reprogramming.
Article in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Water-Saving Drought Survival Phenotype in a Wheat TILLING Mutant Involves Survival-Biased Metabolic and Phosphorylation Reprogramming.Plant, cell & environment · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Drought tolerance in crops often involves trade-offs between water conservation, growth and reproduction. Understanding how water-saving strategies are implemented at physiological and metabolic levels remains critical for improving crop performance under water-limited conditions. Here, we characterise a wheat TILLING mutant, WS1, that exhibits enhanced survival under drought stress. WS1 showed reduced stomatal conductance and transpiration, together with increased carbon isotope discrimination, consistent with reduced water loss. Despite these traits, WS1 displayed weak stomatal responses to exogenous abscisic acid (ABA), indicating that its water-saving behaviour is not primarily explained by canonical ABA signalling. Metabolomic analyses revealed substantial accumulation of proline and changes in nitrogen and carbon metabolism, suggesting a shift toward a survival-oriented metabolic state. Phosphoproteomic profiling further identified distinct phosphorylation patterns associated with energy-related signalling components, including proteins linked to SnRK1 pathways. These molecular features likely reflect an altered energy-sensing and regulatory state rather than direct causal drivers of the phenotype. Notably, WS1 exhibited reduced fertility, indicating a trade-off between survival and reproductive investment. Together, our results suggest that WS1 adopts a water-saving drought survival phenotype characterised by coordinated physiological and metabolic reprogramming, providing a framework for understanding survival-oriented drought responses and resource allocation strategies in wheat.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.