Evidence map›Paper›PMID 42001258›Full record

ArticleJournal of periodontology2026

Impact of leaving periodontal disease untreated on healthcare expenditures: A retrospective cohort study.

Anna Kinugawa, Kenji Takeuchi, Yudai Tamada, Taro Kusama, Futoshi Oda, Megumi Maeda, Hiroe Ohyama, Ken Osaka, Haruhisa Fukuda

Abstract readComparative Study
In one paragraph

Article in Journal of periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna KinugawaDepartment of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Miyagi, Japan.ORCID https://orcid.org/0000-0003-3988-765X
Kenji TakeuchiDepartment of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Miyagi, Japan.ORCID https://orcid.org/0000-0001-8769-8955
Yudai TamadaDepartment of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Miyagi, Japan.ORCID https://orcid.org/0000-0001-6868-4195
Taro KusamaDepartment of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Miyagi, Japan.ORCID https://orcid.org/0000-0001-8683-4484
Futoshi OdaDepartment of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
Megumi MaedaDepartment of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
Hiroe OhyamaDepartment of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Miyagi, Japan.ORCID https://orcid.org/0000-0002-3599-1671
Ken OsakaDepartment of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Miyagi, Japan.
Haruhisa FukudaDepartment of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.

Funding

Grant-in-Aid for Scientific Research (JSPS KAKENHI) from the Japan Society for the Promotion of Science JP23K24557Health Labour Sciences Research Grant from the Ministry of Health, Labour and Welfare, Japan 23FA1022Health Labour Sciences Research Grant from the Ministry of Health, Labour and Welfare, Japan 24FA1020Japan Agency for Medical Research and Development JP23ek0210191JST FOREST Program of the Japan Science and Technology Agency JPMJFR205JJST SPRING program of the Japan Science and Technology Agency JPMJSP2114
6 · The paper itself

Abstract

backgroundThis study aimed to investigate whether healthcare expenditures (HCEs) differed depending on whether the patients left periodontal disease (PD) untreated, despite the need for treatment.

methodsThis study used public PD screening data from a municipality in Japan to identify adults aged ≥ 40 years who were found to require treatment of PD by dentists at PD screening. The presence or absence of periodontal treatment was determined by a dental visit within 180 days after the date of PD screening based on medical claims data. Annual HCE were calculated from cumulative expenditures over 2 years from the date of the presence or absence of periodontal treatment. A generalized linear model with a gamma distribution and log link function was used to calculate the relative cost ratios (RCRs) and 95% confidence intervals (95% CI), and a two-part model was used to predict annual HCEs and the difference in predicted HCEs based on dental treatment.

resultsAmong 652 people (mean age: 62.6 years [1 SD = 9.0], 65.5% women), 9.0% were untreated. After adjusting for the covariates, the RCR for medical, pharmaceutical, and dental costs in the untreated group compared with the treated group were 1.56 (95% CI: 1.02-2.38), 0.95 (95% CI: 0.53-1.70), and 0.14 (95% CI: 0.10-0.19), respectively. The differences in predicted HCEs were $593.5 (95% CI: -280.6, 1467.6) higher for medical, $79.9 (95% CI: -363.6, 523.4) higher for pharmaceutical, and $323.9 (95% CI: -397.3, -250.6) lower for dental.

conclusionLeaving PD untreated was associated with increased HCEs, particularly medical expenditures. PLAIN LANGUAGE SUMMARY: This study looked at whether people who were told by a dentist that they needed care for periodontal disease actually received treatment, and how this affected their healthcare costs. The research followed more than 600 adults in Japan for 2 years, comparing the cumulative healthcare costs of those who received dental care with those who did not. The results showed that people who did not treat their periodontal disease ended up spending more on medical care, even though they spent less on dental care. On average, untreated individuals had medical expenses that were around $600 higher than those who received treatment. This suggests that avoiding dental care for periodontal disease might lead to more serious health problems down the line, which can increase overall healthcare costs. Although skipping dental visits may seem like a way to save money, it could actually lead to higher medical bills in the future. These findings highlight the importance of early dental treatment not just for oral health, but also for managing overall healthcare costs and preventing other health complications.

Indexed as

Health ExpendituresPeriodontal DiseasesAdultAgedCohort StudiesDental CareDrug CostsFemaleHealth Care CostsHumansJapanMaleMiddle AgedRetrospective StudiesUndertreatmentdental public healthepidemiologyhealth care costshealth service researchperiodontal diseasespreventive dentistry

Identifiers

PMID42001258
PMCPMC13568914

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.