ArticlePacing and clinical electrophysiology : PACE2026
PFA Under Deep Sedation and Non-Invasive Monitoring in Atrial Fibrillation Patients With Obstructive Sleep Apnea.
Article in Pacing and clinical electrophysiology : PACE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical data about pulsed field ablation (PFA) under deep sedation among patients with obstructive sleep apnea (OSA) are limited, while the optimal periprocedural monitoring is not established. We report our experience in PFA among patients with atrial fibrillation (AF) and OSA, using a continuous non-invasive respiratory and hemodynamic monitoring protocol.
methodsA total of 32 patients with AF suffering from OSA (mean age 68.5 ±9 years, 31% female) were compared with 60 consecutive patients without OSA. The monitoring protocol comprised continuous beat-to-beat blood pressure recording via an infrared light system and near-infrared spectroscopy for both cerebral and peripheral tissue oximetry. The Acumen Hypotension Prediction Index (HPI) that detects hypotensive trending was also assessed.
resultsThree of the patients with OSA (9%) and four of the controls (6%) developed transient decrease of cerebral saturation during induction to deep sedation, early detected and effectively managed with airway manoeuvres and supplemental oxygen up-titration. In nine patients with OSA (28%) and twenty controls (33%), increased HPI values followed by transient decrease in blood pressure were detected after induction to sedation and/or during PFA, responsive to intravenous fluids. The average time of hypotension was comparable between patients with and without OSA (2.69% vs. 3.23% of the total procedure time, respectively). No serious complications occurred.
conclusionPFA under deep sedation in patients with OSA and AF was not associated with higher incidence of adverse events compared to those without OSA. This is confirmed by a sensitive continuous non-invasive monitoring protocol, which could be further evaluated by dedicated multicenter studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.