Evidence map›Paper›PMID 42001197›Full record

ArticleBMC psychology2026

The extra burden: differential somatization-moderated mediation models of anxiety, depression, and insomnia on quality of life through abnormal illness behavior in Chinese college students.

Liyun Liu, Mingqing Huang, Xiaoyun Liu, Sen Yang, Ping Wu, Zhen Pei, Yanqi Wang, Jialiang Mao, Yibo Wang, Junwu Hu and 1 more

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Article in BMC psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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11 authors.

Liyun LiuAdministrative Department of Standardized Training for Resident Doctors, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Mingqing HuangDepartment of Information Management, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Xiaoyun LiuDepartment of General Practice, The People's Hospital of Changzhi City, Changzhi, 046000, China.
Sen YangDepartment of Osteology, The People's Hospital of Changzhi City, Changzhi, 046000, China.
Ping WuDepartment of Scientific Research, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Zhen PeiDepartment of Student Affairs, Changzhi Medical College, Changzhi, 046000, China.
Yanqi WangDepartment of Scientific Research, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Jialiang MaoDepartment of Cardiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200000, China.
Yibo WangDepartment of Cardiology, Shanghai Second People's Hospital, Shanghai, 200011, China.
Junwu HuDepartment of Psychology, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Long WangDepartment of Neurosurgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China. wanglong@czmc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPsychological distress (anxiety, depression, insomnia) is prevalent among college students, often co-occurring with somatization and abnormal illness behavior (AIB) to impair quality of life (QoL). This study aims to construct moderated mediation models exploring the association between psychological distress and QoL through AIB, and examine the moderating role of somatization, providing evidence for targeted mental health interventions.

methodsA cross-sectional survey of 7,529 Chinese college students was conducted. Anxiety, depression, and insomnia were treated as predictors, AIB as the mediator, somatization as the moderator, and QoL (mental component summary [MCS] and physical component summary [PCS]) as the outcomes.

resultsAfter adjusting for selected covariates, anxiety, depression, and insomnia showed significant negative direct effects on PCS (β = -0.0553, 95%CI: -0.0995 to -0.0111; β = -0.1034, 95%CI: -0.1428 to -0.0641; β = -0.3559, 95%CI: -0.3932 to -0.3185) and MCS (β = -0.5321, 95%CI: -0.5819 to -0.4823; β = -0.4799, 95%CI: -0.5243 to -0.4355; β = -0.4818, 95%CI: -0.5247 to -0.4389), all p < 0.05. AIB significantly mediated the associations of anxiety, depression, and insomnia with PCS and MCS. Somatization moderated all indirect effects: conditional indirect effects were significantly negative at low, moderate, and high levels of somatization, and the negative mediating effects strengthened as somatization increased.

conclusionsAIB mediated the relationship between psychological distress and QoL, and this mediation was moderated by somatization. These findings clarify the psychosomatic correlates of QoL impairment in a non-Western population, informing culturally tailored college mental health strategies and providing implications for clinical assessment and intervention.

Indexed as

AnxietyDepressionIllness BehaviorQuality of LifeSleep Initiation and Maintenance DisordersSomatoform DisordersStudentsAdolescentAdultChinaCross-Sectional StudiesFemaleHumansMaleMediation AnalysisPsychological DistressAbnormal illness behaviorModerated mediation modelPsychological distressQuality of lifeSomatization

Identifiers

PMID42001197
PMCPMC13330162

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.