ArticleBMC veterinary research2026
Antibiotic resistance genes in companion animals and humans driven by the gut microbial communities: composition, distribution, and implications.
Article in BMC veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Neglected ESKAPE Pathogens in Companion Animals: Diagnostic Bias, Zoonotic Blind Spots, and Phytotherapeutic Opportunities.Pathogens (Basel, Switzerland) · 2026Review
- Comparison of Environmental Microbiomes, Resistomes and Plasmidomes from a Human Tertiary Hospital and Companion Animal Veterinary Hospital in London, UK.Antibiotics (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundThe widespread and inappropriate use of antibiotics in both human and veterinary medicine has accelerated the emergence and dissemination of antibiotic resistance genes (ARGs) in various environments. Companion animals, due to their close and prolonged interactions with humans, have increasingly been recognized as potential reservoirs and transmitters of ARGs. However, the extent remains largely unclear to which companion animals influence the diversity and distribution of ARGs in humans. Understanding these interactions is essential for assessing environmental pathways of antibiotic resistance transmission and for developing effective mitigation strategies within the One Health framework. We examined the profiles of ARGs and gut microbial communities among three groups: companion animals, pet owners, and non-pet owners. Quantitative polymerase chain reaction (qPCR) assays were applied to determine the abundance and diversity of representative ARGs, while 16S rRNA gene sequencing was used to characterize the composition and structure of microbial communities. Comparative and correlation analyses were conducted to evaluate the relationships between ARG distribution patterns and microbial community profiles across different host groups.
resultsCompanion animals were found to possess the highest total abundance of ARGs (8.46 × 10
conclusionsOur findings show that pet owners exhibit similar ARG profiles to those in companion animals, suggesting pet ownership may drive convergence in profiles of ARGs. Moreover, these findings provides evidence of potential resistome overlap at the human-animal interface and highlight the need to incorporate companion animals into antimicrobial control programs under a One Health framework.
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Registered trials
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