Evidence map›Paper›PMID 42001107›Full record

Trial reportBMC health services research2026

Using co-design to develop actionable strategies to identify and follow-up on breast cancer survivors in primary care.

Sarah J Fadem, Shawna V Hudson, Benjamin F Crabtree, Jenna Howard, Jennifer R Hemler, Jeanne Ferrante, Lisa Mikesell, Ayana K April-Sanders, Alicja Bator, Denalee M O'Malley

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05400941 (Adapting and Implementing Evidence-based Breast Cancer Follow-up in Primary Care), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05400941 naenrolling by invitationnot on this map

Adapting and Implementing Evidence-based Breast Cancer Follow-up in Primary Care

TypeinterventionalSponsorRutgers, The State University of New JerseyRan2024 to 2026Enrolled910ConditionsCancer, Breast, Health Care UtilizationArmsPractice Led Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah J FademDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA. sjf158@rwjms.rutgers.edu.
Shawna V HudsonDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA.
Benjamin F CrabtreeDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA.
Jenna HowardDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA.
Jennifer R HemlerDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA.
Jeanne FerranteDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA.
Lisa MikesellInstitute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ, 08901, USA.
Ayana K April-SandersDepartment of Biostatistics & Epidemiology, Rutgers School of Public Health, 683 Hoes Lane West, Piscataway, NJ, 08854, USA.
Alicja BatorDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA.
Denalee M O'MalleyDepartment of Family Medicine and Community Health, Research Division, Rutgers Robert Wood Johnson Medical School, 303 George Street, Matrix Plaza I Building, 3rd Floor, New Brunswick, NJ, 08901, USA.

Funding

Diversity Supplement to Adapting and implementing evidence-based breast cancer follow-up in primary careR01CA257197 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI HUDSON, SHAWNA V. · 2021 to 2025
$3.7M
NJ ACTS: A Platform for Translational Science in New Jersey: CTSA K12 Program at Rutgers, Biomedical Health SciencesK12TR004788 · NCATS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI John R. Chan, Ethan A Halm · 2024 to 2026
$2.8M
NCATS NIH HHS K12TR004788NCI NIH HHS R01 CA257197NCI NIH HHS R01CA257197
6 · The paper itself

Abstract

backgroundTranslation of breast cancer survivorship evidence into primary care practice has relied on unidirectional oncology-centric approaches (e.g., care plans, guidelines) that fail to account for the realities of primary care delivery. Implementation challenges are exacerbated by difficulty identifying survivors and a lack of actionable guidelines for screening and treatment of late/long-term effects. Using principles of co-design to tailor implementation strategies has potential to produce actionable strategies for primary care delivery contexts.

methodsGuided by the Exploration, Preparation, Implementation, and Sustainment (EPIS) framework, formative implementation mapping data were collected to inform the development of an interventional prototype to support primary care practices in providing survivorship care for patients with a history of breast cancer: Actionable Follow-up to Enhance suRvivorship in Breast Cancer (AFTER-BC).

resultsAFTER-BC is a primary care focused intervention that includes electronic health record (EHR) integrated tools to create a breast cancer survivor registry and screen for late and long-term effects of treatment. Twenty-six primary care practices were recruited from a large integrated health system with 13 randomized into the initial intervention arm. The AFTER-BC intervention included three virtual learning collaboratives with practice-level champions held over 12 weeks with ongoing bi-weekly virtual facilitation support. Throughout implementation, champions were prompted for feedback and suggestions which were integrated into the AFTER-BC prototype as appropriate and possible. More complex suggestions were documented for future refinement.

conclusionsIn fielding AFTER-BC and incorporating end-user input to refine the intervention components, this study demonstrates the value of co-design principles for initial intervention delivery. For translational challenges where actionable strategies in the primary care context are lacking, creating responsive real-time feedback loops can enhance the contextual appropriateness of interventions.

trial registrationRegistered with ClinicalTrials.gov on June 2, 2022: NCT05400941, https://clinicaltrials.gov/study/NCT05400941 .

Indexed as

Breast NeoplasmsCancer SurvivorsPrimary Health CareElectronic Health RecordsFemaleHumansBreast cancerCancer survivorshipCo-designPrimary careStakeholder engagementTailoring

Identifiers

PMID42001107
PMCPMC13224662

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.