Evidence map›Paper›PMID 42001066›Full record

Trial reportBMC musculoskeletal disorders2026

The effect of experimentally induced acute pain on lumbar movement control: a single blinded three-arm cross-over randomized control trial.

Beate Schüßler, Gabriela Ferreira Carvalho, Tibor Maximilian Szikszay, Patrizia Khan, Stefan Sebastian Niemuth, Carla Nau, Kerstin Luedtke

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Beate SchüßlerDepartment of Physiotherapy, Institute of Health Sciences, Pain and Exercise Research Luebeck (P.E.R.L.), University of Lübeck, Lübeck, Germany. bat.schuessler@gmail.com.
Gabriela Ferreira CarvalhoDepartment of Physiotherapy, Faculty of Health, Medical & Life Sciences, Furtwangen University, Furtwangen, Germany.
Tibor Maximilian SzikszayDepartment of Physiotherapy, Institute of Health Sciences, Pain and Exercise Research Luebeck (P.E.R.L.), University of Lübeck, Lübeck, Germany.
Patrizia KhanDepartment of Physiotherapy, Institute of Health Sciences, Pain and Exercise Research Luebeck (P.E.R.L.), University of Lübeck, Lübeck, Germany.
Stefan Sebastian NiemuthDepartment of Anaesthesiology and Intensive Care, University Medical Center Schleswig-Holstein, Campus Lübeck and University of Lübeck, Lübeck, Germany.
Carla NauDepartment of Anaesthesiology and Intensive Care, University Medical Center Schleswig-Holstein, Campus Lübeck and University of Lübeck, Lübeck, Germany.
Kerstin LuedtkeDepartment of Physiotherapy, Institute of Health Sciences, Pain and Exercise Research Luebeck (P.E.R.L.), University of Lübeck, Lübeck, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-specific low back pain exhibits high prevalence and is commonly correlated with deficits in lumbar movement control. Whether pain precipitates these impairments or arises as their sequela remains uncertain. This study investigates how experimentally induced acute pain influences lumbar movement control.

methodForty-five healthy, pain-free participants underwent three experimental conditions in randomized order: hypertonic saline injection to the lumbar paraspinal muscle (inducing local pain), hypertonic saline injection to the deltoid muscle (inducing remote pain), and isotonic saline injection to the lumbar paraspinal muscle (sham). A standardized, reliable and validated battery of lumbar movement control tests was performed before, during and after each condition and rated by an examiner blinded towards the experimental intervention. Perceived pain intensity was evaluated every 30 s using the numeric rating scale.

resultsWhile initial analysis revealed a significant overall effect (χ

conclusionExperimentally induced acute pain exerted no detectable effect on lumbar movement control. Across analyses, performance remained stable, indicating short-term robustness to transient nociceptive input.

trial registrationDRKS00038877 (retrospectively registered; January 6th, 2026).

Indexed as

Acute PainLow Back PainParaspinal MusclesAdultCross-Over StudiesFemaleHumansLumbosacral RegionMaleMovementPain MeasurementSaline Solution, HypertonicSingle-Blind MethodYoung AdultSaline Solution, HypertonicAcute painExperimental painLow back painMovement controlPain mechanisms

Identifiers

PMID42001066
PMCPMC13094034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.