Evidence map›Paper›PMID 42001063›Full record

ArticleJournal of nanobiotechnology2026

Single-dose X-ray driven persistent activation of nanoprodrugs for radio-chemo-immunotherapy.

Yi-Qun Wu, Dan-Dan Wang, Jia-Mi Li, Jiao-Jiao Ma, Wang Qian, Li He, Bo Wu, Shi-Wen Huang, Jun Feng, Kai Deng and 1 more

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yi-Qun WuDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Dan-Dan WangKey Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Wuhan University, Wuhan, 430072, China.
Jia-Mi LiDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Jiao-Jiao MaDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Wang QianDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Li HeDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Bo WuDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Shi-Wen HuangKey Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Wuhan University, Wuhan, 430072, China.
Jun FengKey Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Wuhan University, Wuhan, 430072, China. fengjun@whu.edu.cn.
Kai DengDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. deng-k@whu.edu.cn.
Yong-Chang WeiDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. weiyongchang@whu.edu.cn.

Funding

the National Natural Science Foundation of China 82202132the Natural Science Foundation of Hubei Province 2024AFB735
6 · The paper itself

Abstract

X-ray triggered local activation of prodrugs is promising for tumor radio-chemo-immunotherapy. However, the insufficient active drugs within tumors under prescribed X-ray doses lead to poor immunogenic effects. Here, we proposed to develop ClO

Indexed as

Antineoplastic AgentsDoxorubicinImmunotherapyNanoparticlesProdrugsAnimalsCell Line, TumorHumansMiceMice, Inbred BALB CX-RaysAntineoplastic AgentsDoxorubicinProdrugsChemotherapyImmunogenicityInflammationPersistent drug releaseRadiotherapy

Identifiers

PMID42001063
PMCPMC13227667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.