ArticleBMC infectious diseases2026
Clinical characteristics and factors associated with in-hospital mortality in psoas abscess: a retrospective cohort study from Vietnam.
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundOver the past decades, the widespread use of advanced imaging has improved detection of psoas abscess (PA), yet evidence from low- and middle-income settings remains limited. We aimed to describe the clinical, etiological and microbiological characteristics of PA and to explore clinically relevant factors associated with in-hospital mortality using data from Vietnam.
methodsWe retrospectively reviewed all inpatients with CT/MRI-confirmed PA at Cho Ray Hospital, Vietnam (January 2020–December 2024). Demographics, comorbidities, presentation, laboratory/imaging findings, microbiology, treatments, and outcomes were extracted. Sepsis/septic shock followed Sepsis-3 definitions.
resultsAmong 233 patients (mean age 52.3 ± 17.5 years; 59.7% male), diabetes was the most common comorbidity (28.8%). Flank pain (55.8%) and fever (39.1%) predominated. Primary PA accounted for 68.2%; spinal sources were most frequent (24.5%) among secondary cases. Cultures were positive in 38.7%. Staphylococcus aureus (41.4%) and Escherichia coli (34.3%) were predominant. Sepsis/septic shock developed in 9.0%, and in-hospital mortality was 5.2%. In exploratory univariable Cox analysis, several clinical variables, including age ≥ 65 years, tachycardia, tachypnea, hypotension, thrombocytopenia, and treatment modality, were associated with in-hospital mortality. Among these, tachypnea and thrombocytopenia appeared particularly clinically relevant as simple bedside indicators of systemic deterioration.
conclusionsIn this large Vietnamese cohort, PA chiefly affected middle-aged and older adults and often presented nonspecifically. In exploratory analysis, tachypnea and thrombocytopenia were identified as clinically relevant bedside markers associated with in-hospital mortality; these findings should be interpreted as hypothesis-generating rather than confirmatory.
trial registrationNot applicable (retrospective study).
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