ArticleBMC infectious diseases2026
Clinical characteristics and outcomes of Candida tropicalis fungemia in patients with hematologic diseases: a single-center retrospective study in China (2018-2024).
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCandida tropicalis has emerged as a significant non-albicans Candida species, particularly in patients with hematologic diseases. However, large-scale data on the clinical characteristics and outcomes of Candida tropicalis fungemia specifically in this high-risk population remain limited, necessitating further investigation.
objectiveTo investigate the epidemiology, clinical characteristics, and prognostic risk factors of Candida tropicalis fungemia in hematology patients.
methodsA retrospective analysis was conducted on clinical data from 65 patients with Candida tropicalis bloodstream infection, confirmed by blood culture, in the hematology department of the First Affiliated Hospital of Soochow University between January 2018 and December 2024.
resultsCandida tropicalis fungemia accounted for 0.69‰ of cases in our hematology department. All infections occurred in patients with hematologic malignancies, primarily acute leukemia. This pathogen demonstrated notably high resistance rates to fluconazole and voriconazole. The overall mortality rate was 29.2%. Univariate analysis identified sex (male), primary disease status, positive (1,3)-β-D-glucan test, positive procalcitonin test, organ damage, requirement for respiratory support, and the presence of shock as risk factors for mortality. However, multivariate analysis confirmed that only the primary disease status was an independent prognostic factor.
conclusionCandida tropicalis is a significant pathogen in the hematology setting, particularly among patients with hematologic malignancies, causing bloodstream infections with high mortality. Our findings suggest that effective management of the underlying hematologic disease is crucial for improving patient survival outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.