Evidence map›Paper›PMID 41999683›Full record

ArticleThe journal of nutrition, health & aging2026

Association between dietary protein intake and frailty index among home-dwelling older adults; an 8-year follow-up study.

Pia Bålsrud, Stine M Ulven, Anette Hjartåker, Inger Ottestad, Kjetil Retterstøl, Ursula Schwab, Jacob J Christensen, Magne Thoresen, Kirsten B Holven

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Article in The journal of nutrition, health & aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Pia BålsrudDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Stine M UlvenDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Anette HjartåkerDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Inger OttestadDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; Clinical Nutrition, Department of Clinical Service, Division of Cancer Medicine, Oslo University Hospital, Oslo, Norway.
Kjetil RetterstølDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; The Lipid Clinic, Oslo University Hospital, Oslo, Norway.
Ursula SchwabInstitute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; Department of Medicine, Endocrinology and Clinical Nutrition, Kuopio University Hospital, Kuopio, Finland.
Jacob J ChristensenDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Magne ThoresenDepartment of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Kirsten B HolvenDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; Norwegian National Network on Familial Hypercholesterolemia, Oslo University Hospital, Oslo, Norway. Electronic address: k.b.holven@medisin.uio.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe World's population is getting older, and healthy behavior such as a healthy diet may prevent the development of frailty and promote healthy ageing. In this study, we aimed to investigate the association between dietary protein intake and longitudinal changes in frailty among older, home-dwelling subjects.

methodData were obtained from 130 home-dwelling, Norwegian older adults (70+) at baseline and after 8-year follow-up. Frailty was measured by a frailty index (FI) based on an accumulation of 38 deficits, scored 0-1. Dietary protein intake was collected by 2 × 24-h recall per visit. The association between dietary intake at baseline and change in FI was analysed by linear regression modelling. Changes in diet and changes in FI between the two visits were analyzed by Spearman's rank correlation coefficient.

resultsThe FI score significantly increased from baseline to follow-up (0.12 vs 0.2, p < 0.001), and more subjects were categorised as frail at the follow-up visit (3% vs 33%, p < 0.001). Overall, there was no significant association between dietary protein intake at baseline or change in dietary intake and change in FI score. We did, however, observe a decreased intake of protein (E %) and meat (g) after 8-year follow-up.

conclusionsOur findings suggest that frailty accelerates with age, independent of dietary protein intake. A healthy diet may delay the rate of frailty, however, even if the dietary intake of protein remains stable after 8-year follow-up, it could not prevent the frailty process in our study population. Thus, more studies are needed to describe what factors that might accelerate or prevent the accumulation of frailty deficits with advancing years.

Indexed as

DietDietary ProteinsFrail ElderlyFrailtyGeriatric AssessmentAgedAged, 80 and overFemaleFollow-Up StudiesHumansIndependent LivingMaleNorwayDietary ProteinsFrailty indexLongevityNutritionOlder adultsProtein

Identifiers

PMID41999683
PMCPMC13098404

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