Evidence map›Paper›PMID 41999590›Full record

ArticleAllergy2026

Identification of Shared Regulators of IgE- and MRGPRX2-Dependent Degranulation in Human Mast Cells.

Jelle Folkerts, Paula van Tienen, Marjolein J W de Bruijn, Wilfred F J van IJcken, Rudi W Hendriks, Ralph Stadhouders, See-Ying Tam, Stephen J Galli

Abstract readLetter
In one paragraph

Article in Allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jelle FolkertsDepartment of Pathology, Stanford University School of Medicine, California, USA.ORCID https://orcid.org/0000-0002-1014-330X
Paula van TienenDepartment of Pathology, Stanford University School of Medicine, California, USA.
Marjolein J W de BruijnDepartment of Pulmonary Medicine, Erasmus MC Rotterdam, the Netherlands.
Wilfred F J van IJckenCenter for Biomics, Erasmus MC Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-0421-8301
Rudi W HendriksDepartment of Pulmonary Medicine, Erasmus MC Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0003-2291-0382
Ralph StadhoudersDepartment of Pulmonary Medicine, Erasmus MC Rotterdam, the Netherlands.
See-Ying TamDepartment of Pathology, Stanford University School of Medicine, California, USA.
Stephen J GalliDepartment of Pathology, Stanford University School of Medicine, California, USA.

Funding

Tracking allergen specific T cells in multi-food allergyU19AI104209 · NIAID · STANFORD UNIVERSITY · PI CHINTHRAJAH, R. SHARON · 2013 to 2025
$17.3M
Role of nociceptive sensory neuron/mast cell interactions in cutaneous allergic inflammationR01AI132494 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2017 to 2021
$2.4M
RabGEF1 in MyD88 signaling, skin immunity, and atopic dermatitisR01AR067145 · NIAMS · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2015 to 2019
$1.9M
European Molecular Biology Organization 5868Lung Foundation Netherlands 4.1.18.226Lung Foundation Netherlands 4.2.19.041JOLung Foundation Netherlands 6.1.25.069Nederlandse Organisatie voor Wetenschappelijk Onderzoek 09120232310020Nederlandse Organisatie voor Wetenschappelijk Onderzoek 09150172010068NIAID NIH HHS R01 AI132494NIAID NIH HHS U19 AI104209NIAMS NIH HHS R01 AR067145NIH HHS R01 AI132494NIH HHS R01 AR067145NIH HHS U19AI104209Stichting Astma Bestrijding 2022/007United States-Israel Binational Science Foundation 2017182
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

degranulationdifferential gene expressionhistone methylationhuman mast cellsnegative regulators

Identifiers

PMID41999590
PMCPMC13466246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.