Evidence map›Paper›PMID 41999560›Full record

ArticleJournal of gastrointestinal cancer2026

Survival Impact of Adjuvant Chemotherapy on Stage IB Gastric Cancer Patients After Radical Surgery.

Yi-Fu Chen, Hao-Wei Kou, Tsung-Hsing Chen, Puo-Hsien Le, Chia-Jung Kuo, Shang-Yu Wang, Wen-Chi Chou, Ta-Sen Yeh, Jun-Te Hsu

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Article in Journal of gastrointestinal cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yi-Fu ChenDepartment of General Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Hao-Wei KouDepartment of General Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Tsung-Hsing ChenDepartment of Gastroenterology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Puo-Hsien LeDepartment of Gastroenterology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Chia-Jung KuoDepartment of Gastroenterology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Shang-Yu WangDepartment of General Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Wen-Chi ChouDepartment of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ta-Sen YehDepartment of General Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Jun-Te HsuDepartment of General Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan. hsujt2813@cgmh.org.tw.

Funding

Chang Gung Medical Research Program, Taiwan CMRPG3I0103
6 · The paper itself

Abstract

purposeRadical surgery is the primary treatment for localized gastric cancer (GC), but the benefit of adjuvant chemotherapy in stage IB GC remains unclear. This study evaluates its impact on recurrence and survival post-gastrectomy.

methodsWe retrospectively analyzed 357 patients with pathological T1N1M0 or T2N0M0 GC who underwent radical gastrectomy (1994-2020). Clinicopathological data were collected, and propensity score matching (PSM) was used to minimize selection bias.

resultsThe chemotherapy group was younger (p = 0.007), had lower Charlson comorbidity index scores (p = 0.006), more partial gastrectomies (p = 0.048), and higher lymphovascular invasion rates (p = 0.023). No significant differences were observed in disease-free (p = 0.346) or cancer-specific survival (p = 0.358) between groups, even after PSM.

conclusionsAdjuvant chemotherapy did not improve survival. Large-scale randomized trials are needed to clarify its role in stage IB GC.

Indexed as

GastrectomyNeoplasm Recurrence, LocalStomach NeoplasmsAgedChemotherapy, AdjuvantFemaleHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesSurvival RateAdjuvant chemotherapyGastric cancerStage IBSurvival

Identifiers

PMID41999560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.