Evidence map›Paper›PMID 41999545›Full record

ArticleJournal of epidemiology and global health2026

Global Health Reform through a Regional Lens: The Middle East and Central Asia Perspective.

Yousef Khader, Mohannad Al Nsour, Randa Saad, Antonio Sarria-Santamera, Nader Kabbani, Aruzhan Montayeva, Kuanysh Yergaliyev, Laura Kozhageldiyeva, Nejla Ben Mimoune, Theresa Madubuko and 1 more

Abstract read
In one paragraph

Article in Journal of epidemiology and global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yousef KhaderDepartment of Public Health, Faculty of Medicine, Jordan University of Science and Technology Irbid, Irbid, Jordan. yskhader@just.edu.jo.
Mohannad Al NsourEastern Mediterranean Public Health Network (EMPHNET), Amman, Jordan.
Randa SaadEastern Mediterranean Public Health Network (EMPHNET), Amman, Jordan.
Antonio Sarria-SantameraDepartment of Biomedical Sciences, Nazarbayev University School of Medicine, 5/1 Kerey and Zhanibek Khandar Str, Astana, Republic of Kazakhstan.
Nader KabbaniMiddle East Council on Global Affairs, Burj Al Mana, 3rd Floor, West Bay Doha, Qatar.
Aruzhan MontayevaDepartment of Biomedical Sciences, Nazarbayev University School of Medicine, 5/1 Kerey and Zhanibek Khandar Str, Astana, Republic of Kazakhstan.
Kuanysh YergaliyevDepartment of Biomedical Sciences, Nazarbayev University School of Medicine, 5/1 Kerey and Zhanibek Khandar Str, Astana, Republic of Kazakhstan.
Laura KozhageldiyevaDepartment of Biomedical Sciences, Nazarbayev University School of Medicine, 5/1 Kerey and Zhanibek Khandar Str, Astana, Republic of Kazakhstan.
Nejla Ben MimouneMiddle East Council on Global Affairs, Burj Al Mana, 3rd Floor, West Bay Doha, Qatar.
Theresa MadubukoMiddle East Council on Global Affairs, Burj Al Mana, 3rd Floor, West Bay Doha, Qatar.
Shadi SalehGlobal Health Institute, American University of Beirut, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReform of the global health architecture has emerged as a central policy priority, yet regionally grounded perspectives that translate critical analysis into actionable directions remain limited. This gap is particularly evident in the Middle East and Central Asia (MECA), a region characterized by diverse political and economic contexts, fragile and emergency-prone settings, and wide variation in health system capacity and governance. This study aimed to assess MECA stakeholders’ perspectives on the strengths and weaknesses of the current global health architecture, articulate a shared regional vision for future governance, and identify and prioritize reform directions relevant to the MECA context.

methodsA mixed-methods, multi-phase deliberative policy dialogue approach was employed. Data were collected through semi-structured interviews with 47 key informants, an online survey of 248 stakeholders from 17 MECA countries, and a two-day regional dialogue involving 49 senior leaders from 14 countries. The exercise culminated in a structured prioritization completed by 34 participants. Qualitative data were analyzed thematically using a hybrid inductive–deductive approach, quantitative data were summarized descriptively, and findings were triangulated across phases.

resultsFindings were synthesized into five priority reform directions reflecting shared concerns around governance imbalances, fragmented financing, and limited regional agency. Aligning global health financing and technical support with nationally defined priorities emerged as the top priority, selected by over 90% of participants in the prioritization exercise. Strengthening regional leadership and enhancing regional collaboration mechanisms were each prioritized by approximately 70% of participants. Strengthening regional data and digital systems as shared public goods was prioritized by 69%, while reinforcing national leadership for integrated, primary health care (PHC)–centered systems was prioritized by 63%. Across reform areas, participants emphasized strengthening and connecting existing institutions rather than creating new structures and highlighted the importance of clear implementation frameworks, accountability mechanisms, and measurable progress indicators.

conclusionsFrom a MECA perspective, effective global health reform requires a shift away from fragmented, externally driven models toward more regionally anchored, country-led, and integrated systems grounded in shared accountability. This includes rebalancing decision-making power, improving coherence across governance and financing mechanisms, and strengthening national and regional ownership of health priorities. These findings provide an empirically grounded regional perspective to inform ongoing global discussions on building more equitable, resilient, and responsive health systems.

Indexed as

Global HealthHealth Care ReformHealth PolicyAsia, CentralHealth PrioritiesHumansMiddle EastPublic Health InfrastructureQualitative ResearchAccountabilityDigital public goodsGlobal health financingGlobal health governanceGlobal health reformHealth system integrationHealth system resilienceMiddle East and Central Asia (MECA)Policy dialoguePrimary health careRegional governance

Identifiers

PMID41999545
PMCPMC13222919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.