Evidence map›Paper›PMID 41999542›Full record

ArticleCEN case reports2026

A case of hypertensive emergency in a patient who had a history of very low birth weight.

Yoichi Kadoh, Jun Yoshino, Tomohiro Oka, Fumika Kamei, Ai Uchida, Maki Hanada, Mamiko Nagase, Daisuke Niino, Takeshi Kanda

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in CEN case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yoichi KadohDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Jun YoshinoDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan. jyoshino@med.shimane-u.ac.jp.ORCID 0000-0001-9833-4356
Tomohiro OkaDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Fumika KameiDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Ai UchidaDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Maki HanadaDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Mamiko NagaseDepartment of Functional Pathology, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.
Daisuke NiinoDepartment of Functional Pathology, Faculty of Medicine, Shimane University, Izumo, Shimane, Japan.
Takeshi KandaDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low birth weight (LBW) is a risk factor for development of hypertension and chronic kidney disease in adulthood. Here, we report the case of a forty-year-old man with a history of very low birth weight (VLBW) (1300 g) who had hypertensive emergency (233/142 mmHg), acute kidney injury (AKI) (serum creatinine, 8.47 mg/dL), elevated plasma renin activity (102 ng/mL/h), and posterior reversible encephalopathy syndrome. He received temporary hemodialysis but was eventually liberated following intensive antihypertensive therapy. A renal biopsy revealed focal segmental glomerulosclerosis (FSGS) with endothelial injury. In addition, the patient had pre-existing, undertreated hypertension. Taken together, the reduced nephron number and impaired vascular development due to LBW may be involved in the development of adult-onset, near fatal hypertensive emergency and subsequent AKI in our case. This case reinforces the long-term cardio-renal risks associated with LBW and illustrates the importance of evaluating perinatal history in the diagnostic workup and successful management of adult-onset nephropathy.

Indexed as

Acute Kidney InjuryGlomerulosclerosis, Focal SegmentalHypertensionInfant, Very Low Birth WeightAdultAntihypertensive AgentsHumansHypertensive CrisisKidneyMalePosterior Leukoencephalopathy SyndromeRenal DialysisRisk FactorsAntihypertensive AgentsAcute kidney injuryHypertensionHypertensive emergencyLow birth weight

Identifiers

PMID41999542
PMCPMC13091823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.