Evidence map›Paper›PMID 41999428›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Diosgenin-loaded niosomes ameliorate cadmium-induced neurotoxicity and endocrine disruption in female rats through modulation of oxidative stress, apoptosis, and inflammatory markers.

Kanza Hashmi, Ammara Saleem, Shakila Sabir, Shahana Ehsan, Aisha Mobashar, Muhammad Imran Khan, Shahnaz, Zulcaif Ahmad, Muhammad Furqan Akhtar, Musaab Dauelbait and 5 more

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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kanza HashmiRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Pakistan.
Ammara SaleemDepartment of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad, Pakistan. ammarasaleem@gcuf.edu.pk.
Shakila SabirRiphah Institute of Pharmaceutical Sciences, Riphah International University, Faisalabad Campus, Faisalabad, Pakistan.
Shahana EhsanDepartment of Chemistry, Lahore College for Women University, Lahore, Pakistan.
Aisha MobasharDepartment of Pharmacology, Faculty of Pharmacy, Faculty of Health Sciences, The University of Lahore, Equator University of Science and Technology, Lahore, Pakistan.
Muhammad Imran KhanRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Pakistan.
ShahnazDepartment of Chemistry, Lahore College for Women University, Lahore, Pakistan.
Zulcaif AhmadDepartment of Pharmacy, University of Rasul, Mandi Bahauddin 50380, Pakistan.
Muhammad Furqan AkhtarRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Pakistan. furqan.pharmacist@gmail.com.
Musaab DauelbaitUniversity of Bahr El Ghazal, Freedowm Stree, Wau 91113 South, Sudan. musaabelnaim@gmail.com.
Amir BouallegueLaboratory of Food Oral Processing, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, 310018, China.
Esmael M AlyamiDepartment of Biology, College of Science, King Khalid University, PO Box 960, 61421, Asir, Abha, Saudi Arabia.
Ohoud A AlghamdiDepartment of Biology, College of Science, King Khalid University, PO Box 960, 61421, Asir, Abha, Saudi Arabia.
Gehan M ElossailyDepartment of Basic Medical Sciences, College of Medicine, AlMaarefa University, 13713, DiriyahRiyadh, Saudi Arabia.
Khalid S AlmaaryDepartment of Botany and Microbiology, College of Science, Saudi Arabia, King Saud University, P. O. BOX 2455, Riyadh, 11451, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to formulate diosgenin-loaded niosomes (DGN) and evaluate their protective effects against cadmium chloride (CdCl

Indexed as

Cadmium ChlorideDiosgeninNeuroprotective AgentsNeurotoxicity SyndromesOxidative StressAnimalsAntioxidantsApoptosisBrainEndocrine DisruptorsFemaleInflammationLiposomesRatsRats, WistarAntioxidantsCadmium ChlorideDiosgeninEndocrine DisruptorsLiposomesNeuroprotective AgentsCadmium toxicityDiosgeninEndocrine disruptionInflammationNiosomesOxidative stress

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.