Evidence map›Paper›PMID 41999370›Full record

ArticleJACC. Case reports2026

Sinus of Valsalva Aneurysm: A Rare Mechanical Cause of Right Ventricular Outflow Tract Obstruction.

Akanimo Usen Antia, Muhammad Usman Almani, Behnam Bozorgnia, Antonio Chamoun

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Akanimo Usen AntiaDivision of Cardiovascular Disease, Department of Medicine, Jefferson Einstein Hospital, Philadelphia, Pennsylvania, USA. Electronic address: akanimousenantia@gmail.com.
Muhammad Usman AlmaniDivision of Cardiovascular Disease, Department of Medicine, Jefferson Einstein Hospital, Philadelphia, Pennsylvania, USA.
Behnam BozorgniaDivision of Cardiovascular Disease, Department of Medicine, Jefferson Einstein Hospital, Philadelphia, Pennsylvania, USA.
Antonio ChamounDivision of Cardiovascular Disease, Department of Medicine, Jefferson Einstein Hospital, Philadelphia, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSinus of Valsalva aneurysm (SOVA) is an infrequent condition commonly affecting the right coronary sinus. It is typically asymptomatic unless it compresses or ruptures into nearby structures. CASE SUMMARY: A 52-year-old man presented to the emergency department with clinical features of heart failure. Transthoracic echocardiography revealed a large SOVA with associated aortic regurgitation (AR), right ventricular outflow tract obstruction (RVOTo), and biventricular dysfunction. Given concern for impending rupture and hemodynamic compromise, the patient was transferred to a tertiary center with a dedicated aortic team for surgical repair. DISCUSSION: This is a case of a right saccular SOVA complicated by severe AR, RVOTo, and biventricular failure. Multimodality imaging is needed to define its anatomic extent and functional effect on neighboring structures. Surgical repair is preferred. TAKE-HOME MESSAGES: Unruptured giant SOVA can cause severe AR and RVOTo, leading to acute heart failure and mimicking myocardial infarction. Multimodality imaging and early referral to a specialized centers are critical for timely surgical management.

Indexed as

acute heart failureaortaaortic valveright-sided catheterizationright ventricle

Identifiers

PMID41999370
PMCPMC13221885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.