Evidence map›Paper›PMID 41999141›Full record

ArticleOrthodontics & craniofacial research2026

Accuracy of Mandibular Dentition Distalisation With Invisalign in Class III Malocclusion: A Pilot Study Using CBCT Superimposition.

Hsin-Yu Wang, Jui-Sheng Sun, Chang-Yu Ku, Shih-Jaw Tsai, Chin-Hao Chang, Jung Fang Liang, Bing-Wu Shee, Jenny Zwei-Chieng Chang

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Article in Orthodontics & craniofacial research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hsin-Yu WangSchool of Dentistry, College of Medicine, National Taiwan University, Taipei City, Taiwan.
Jui-Sheng SunDepartment of Orthopedic Surgery, National Taiwan University Hospital, Taipei City, Taiwan.ORCID https://orcid.org/0000-0001-6549-2171
Chang-Yu KuSchool of Dentistry, College of Medicine, National Taiwan University, Taipei City, Taiwan.
Shih-Jaw TsaiDepartment of Dentistry, National Taiwan University Hospital, Taipei City, Taiwan.
Chin-Hao ChangDepartment of Medical Research, National Taiwan University Hospital, Taipei City, Taiwan.
Jung Fang LiangClinical Trial Center, National Taiwan University Hospital, Taipei City, Taiwan.
Bing-Wu SheeDepartment of Orthopedic Surgery, Landseed International Hospital, Taoyuan City, Taiwan.
Jenny Zwei-Chieng ChangSchool of Dentistry, College of Medicine, National Taiwan University, Taipei City, Taiwan.ORCID https://orcid.org/0000-0002-0376-3199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBy integrating digital models with cone beam computed tomography (CBCT) images and registration on stable hard tissue regions for superimposition, we aimed to enable a more precise and detailed analysis of Invisalign treatment on Class III malocclusion. MATERIALS AND

methodsDigital models of 12 Class III adults at pretreatment (T1) and posttreatment (T2) were integrated with maxillofacial CBCT images. The T1 and T2 CBCT images were superimposed using voxel-based registration of stable cranial base structures to assess the three-dimensional movement of the maxillary teeth and positional changes of the mandible. Mandibular tooth movement was evaluated by superimposition of the mandibular CBCT images, registered on the symphysis and mandibular body. The virtual planning model created by ClinCheck was superimposed based on its position relative to the T1 digital model.

resultsThe median accuracy of distal movement for the mandibular first molar cusps ranged from 26.72% to 33.87%. With miniscrew anchorage, the accuracy ranged from 39.28% to 44.66%. Actual distal movement averaged 0.62 ± 0.82 mm to 0.80 ± 0.89 mm with Class III elastics, and 2.02 ± 1.71 mm to 2.29 ± 1.53 mm with miniscrews. The maxillary incisors significantly proclined more with Class III elastic traction. No significant positional changes in mandibular anatomical landmarks were observed during treatment with miniscrew anchorage, whereas the use of Class III elastics led to significant positional changes in the condyle head.

conclusionInvisalign treatment may not reach the expected efficacy in mandibular dentition distalisation, especially when skeletal anchorage is absent.

Indexed as

Cone-Beam Computed TomographyMalocclusion, Angle Class IIIMandibleTooth Movement TechniquesBone ScrewsCephalometryFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMaleOrthodontic Anchorage ProceduresPatient Care PlanningPilot ProjectsYoung AdultCBCT analysisclass III malocclusionInvisalign treatment

Identifiers

PMID41999141
PMCPMC13485232

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.