Evidence map›Paper›PMID 41999063›Full record

ArticleHuman brain mapping2026

Linking GABAergic and Dopaminergic Neurotransmission: Effects on Neural Activity During Human Speech Control.

Giovanni Battistella, Kristina Simonyan

Abstract read
In one paragraph

Article in Human brain mapping, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giovanni BattistellaDepartment of Otolaryngology-Head & Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Kristina SimonyanDepartment of Otolaryngology-Head & Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-7444-0437

Funding

Understanding disorder-specific neural pathophysiology in laryngeal dystonia and voice tremorP50DC019900 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Kristina Simonyan · 2021 to 2026
$11.9M
Imaging genetics of spasmodic dysphoniaR01DC011805 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Kristina Simonyan · 2012 to 2026
$8.8M
Role of neurotransmission and functional CNS networks in spasmodic dysphoniaR00DC009629 · NIDCD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SIMONYAN, KRISTINA · 2009 to 2012
$955k
NIDCD NIH HHS K99/R00DC009629NIDCD NIH HHS P50DC01990NIDCD NIH HHS P50 DC019900NIDCD NIH HHS R00 DC009629NIDCD NIH HHS R01 DC011805NIDCD NIH HHS R01DC011805
6 · The paper itself

Abstract

Decades of research were instrumental in identifying the brain function controlling speech production. However, our understanding of the regulation of neuronal excitability via neurotransmission during speaking remains scant as the role of the inhibitory GABAergic system in controlling speech production is unknown. Using PET with [

Indexed as

BrainDopaminegamma-Aminobutyric AcidSpeechSynaptic TransmissionAdultBrain MappingFemaleFlumazenilHumansMagnetic Resonance ImagingMalePositron-Emission TomographyRacloprideReceptors, GABA-AYoung AdultDopamineFlumazenilgamma-Aminobutyric AcidRacloprideReceptors, GABA-A

Identifiers

PMID41999063
PMCPMC13090582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.