Evidence map›Paper›PMID 41999045›Full record

ReviewChemical record (New York, N.Y.)2026

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems.

Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni

Abstract readReview
In one paragraph

Review in Chemical record (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Romelly Eugenia Rojas RamírezDepartment of Biochemistry and Molecular Biology, UFSM, Santa Maria, Brazil.ORCID 0000-0002-8103-6675
Tielle Moraes de AlmeidaDepartment of Physics, UFSM, Santa Maria, Brazil.ORCID 0000-0003-2366-8428
Daiani Canabarro LeiteDepartment of Physics, UFSM, Santa Maria, Brazil.ORCID 0000-0003-1197-8437
Gilson ZeniDepartment of Biochemistry and Molecular Biology, UFSM, Santa Maria, Brazil.ORCID 0000-0003-1290-6478

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 404471/2023-4Coordenação de Aperfeiçoamento dePessoal de Nível Superior AUXPE# 1333/2023Coordenação de Aperfeiçoamento dePessoal de Nível Superior PROEX# 88881.844988/2023-01Fundação de Amparo à Pesquisa do Estado do RioGrande do Sul 21/2551-0002314-7
6 · The paper itself

Abstract

In recent years, publications on organoselenium compounds have increased markedly, expanding their applications in therapeutic, nutraceutical, agricultural, and environmental fields. However, intrinsic properties such as high lipophilicity and chemical reactivity often limit their bioavailability and therapeutic performance. Advances in self-assembled nanostructures have enabled more efficient delivery, improving solubility and bioavailability while reducing toxicity. This review is the first to focus specifically on the physicochemical interactions governing the stability and performance of organoselenium-based nanostructures. We analyze recent formulations, emphasizing hydrophobic, van der Waals, electrostatic, and hydrogen bonding interactions that control nanocarrier behavior. Additionally, we discuss emerging strategies and future applications for the rational design of safer and more effective organoselenium delivery systems.

Indexed as

Drug CarriersNanostructuresOrganoselenium CompoundsHumansHydrogen BondingHydrophobic and Hydrophilic InteractionsSolubilityDrug CarriersOrganoselenium Compoundsforcesnanocarriersorganoseleniumsolubilitystabilization

Identifiers

PMID41999045
PMCPMC13387948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.