Evidence map›Paper›PMID 41998814›Full record

ArticleVeterinary ophthalmology2026

Comparison of Corneal Endothelial Imaging Techniques by Specular Microscopy in Unsedated Healthy Dogs.

Hyunwoo Suk, Minju Kim, Dohyeong Kim, Seonmi Kang, Kangmoon Seo

Abstract readComparative Study
In one paragraph

Article in Veterinary ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyunwoo SukDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0009-0008-4840-6532
Minju KimDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0009-0000-4424-745X
Dohyeong KimDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0009-0001-7122-5149
Seonmi KangDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-8017-0891
Kangmoon SeoDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-6645-7116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare unsedated noncontact specular microscopy imaging techniques for the canine corneal endothelium and identify the most effective technique. ANIMALS STUDIED: Nineteen eyes of 10 systemically healthy, staff-owned dogs with clinically normal corneas were studied. PROCEDURE: Six imaging groups were divided according to the different techniques used in all eyes: central focusing, with (CP) or without (CN) induction of an indirect pupillary light reflex (PLR); peripheral focusing with (PP) or without (PN) an indirect PLR; PP with application of a contact lens (CL); and gaze fixation with a treat (GF). The success rates, imaging times, and endothelial cell indices were compared.

resultsSuccess rates differed significantly among the techniques, with PP and CL achieving significantly higher success rates than CN. When only successful images were analyzed, the mean imaging time showed no statistically significant differences between the groups. In the sensitivity analysis, PP required significantly shorter imaging times than CN and PN. The Endothelial cell indices (cell count, endothelial density, and hexagonality) did not differ significantly among the techniques.

conclusionsPeripheral focusing combined with the induction of an indirect PLR (PP) achieved significantly higher success rates and shorter imaging times than other techniques, suggesting that this technique provides the most reliable and efficient approach for evaluating the canine corneal endothelium with noncontact specular microscopy under unsedated conditions.

Indexed as

Endothelium, CornealMicroscopyAnimalsDogsFemaleMalecaninecorneal endothelial dystrophycorneal endotheliumspecular microscopyspecular reflectionunsedated

Identifiers

PMID41998814
PMCPMC13090425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.