Evidence map›Paper›PMID 41998696›Full record

ArticleTrials2026

Efficacy of distress tolerance techniques of dialectical behavior therapy in persons with obsessive-compulsive disorder: a study protocol for a randomized controlled trial.

Mohit Kumar, Vijender Singh, Ranjit Kumar, Abhijit R Rozatkar, Amit Kumar Soni, Sanjay Kumar, Khusboo, Vinit Kumar Singh, Rounak Chatterjee

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mohit KumarAll India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India. mohit.cpsy@aiimsbhopal.edu.in.ORCID http://orcid.org/0000-0002-9831-0546
Vijender SinghAll India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Ranjit KumarGwalior Mansik Aarogyashala, Gwalior, Madhya Pradesh, India.
Abhijit R RozatkarAll India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Amit Kumar SoniGovernment MLB Girls PG College, Kila Bhawan, Devi Ahilya Univesity, Indore, Mahdya Pradesh, India.
Sanjay KumarInstitute of Mental Health Amritsar, Panjab, India.
KhusbooChirayu Medical College & Hospital, Bhopal, Madhya Pradesh, India.
Vinit Kumar SinghAll India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Rounak ChatterjeeAll India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObsessive-compulsive disorder (OCD) is a chronic and debilitating mental health condition that significantly impairs the quality of life. Although cognitive-behavioral therapy (CBT), particularly exposure and response prevention (ERP), is considered the gold standard, many patients remain symptomatic or find these approaches challenging due to emotional and cognitive barriers. Distress tolerance techniques (DTT), a component of dialectical behavior therapy (DBT), have demonstrated efficacy in various conditions, including substance dependence, binge eating, and depression, by managing negative emotional states and enhancing coping mechanisms beyond their original focus on borderline personality disorder. However, the application of DTT in the treatment of patients with OCD has not been extensively explored. This study aims to evaluate the efficacy of DTT in reducing OCD severity and improving psychological outcomes.

methodsThis prospective, single-center, open-label randomized controlled trial will recruit 80 adults (18-40 years) diagnosed with OCD (ICD-10 criteria, Y-BOCS score ≥ 16) from the Department of Psychiatry, All India Institute of Medical Sciences, Bhopal. Participants will be randomized 1:1 using a random number table to either the intervention or active control group. Participants in the intervention group will engage in a 12-week structured DTT program specifically tailored for obsessive-compulsive disorder (OCD), whereas those in the active control group will undergo standard treatment of exposure and response prevention (ERP). The primary outcome will be OCD severity, measured using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). Secondary outcomes included distress tolerance (measured using the Distress Tolerance Scale), depressive symptoms (measured using the Beck Depression Inventory), coping strategies (measured using the Dialectical Behavior Therapy-Ways of Coping Checklist), mindfulness (measured using the Kentucky Inventory of Mindfulness Skills), and acceptance (measured using the Acceptance and Action Questionnaire-II). Outcomes for the treatment groups will be evaluated before randomization (baseline, T1) and 12 weeks (end of treatment, T2). The protocol was approved by the Institute Ethical Committee (approval number) and was performed in strict adherence to the Declaration of Helsinki formulated by the World Medical Association. DISCUSSION: This trial will explore the efficacy of distress tolerance techniques in patients with OCD. This study will provide evidence for a therapeutic approach that addresses the limitations of traditional CBT and improves outcomes for patients with OCD.

trial registrationCentral Trial Register of India CTRI/2024/09/073672. Registered on 21 December 2024.

Indexed as

Dialectical Behavior TherapyObsessive-Compulsive DisorderPsychological DistressAdaptation, PsychologicalAdolescentAdultCoping SkillsFemaleHumansIndiaMaleProspective StudiesRandomized Controlled Trials as TopicSeverity of Illness IndexTime FactorsTreatment OutcomeCognitive-behavior therapyDialectical behavior therapyDistress tolerance techniquesObsessive–compulsive disorderRandomized controlled trial

Identifiers

PMID41998696
PMCPMC13214233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.