Evidence map›Paper›PMID 41998534›Full record

ArticleBMC geriatrics2026

Cognitive frailty and associated factors in older adults with type 2 diabetes in rural Vietnam.

Ngan Thi Kim Duong, Linh Vu Huyen Ha, Thanh Xuan Nguyen, Thu Thi Hoai Nguyen, Huong Thi Thu Nguyen, Ngoc Huy Nguyen, Huyen Thi Thanh Vu

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Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Ngan Thi Kim DuongHanoi Medical University, No 1 Ton That Tung, Hanoi, Hanoi, Vietnam.
Linh Vu Huyen HaHanoi Medical University, No 1 Ton That Tung, Hanoi, Hanoi, Vietnam.
Thanh Xuan NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, Hanoi, Vietnam.
Thu Thi Hoai NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, Hanoi, Vietnam.
Huong Thi Thu NguyenHanoi Medical University, No 1 Ton That Tung, Hanoi, Hanoi, Vietnam.
Ngoc Huy NguyenThe People's Committee of Phu Tho Province, Phu Tho, Vietnam.
Huyen Thi Thanh VuHanoi Medical University, No 1 Ton That Tung, Hanoi, Hanoi, Vietnam. vuthanhhuyen11@hmu.edu.vn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCognitive frailty, defined as the co-occurrence of frailty and cognitive impairment in the absence of dementia, is a strong predictor of adverse health outcomes in older adults. However, evidence on cognitive frailty among older adults with type 2 diabetes mellitus (T2DM) in low- and middle-income countries remains limited. This study aimed to determine the prevalence of cognitive frailty and its associated factors among older adults with T2DM in rural Vietnam.

methodsWe conducted a cross-sectional study among outpatients aged ≥ 60 years with T2DM at a provincial hospital in Phu Tho, Vietnam, from July to December 2024. Cognitive frailty was defined as the presence of both frailty (Fried phenotype) and cognitive impairment (Mini-Cog test score < 3) without dementia. Sociodemographic, clinical, diabetes-related, and geriatric variables were collected. Multivariable logistic regression was used to identify independent factors associated with cognitive frailty.

resultsAmong 840 participants (mean age 73.4 ± 6.8 years; 56.8% female), the prevalence of cognitive frailty was 4.5%, while 9.4% had physical frailty alone. Cognitive frailty was independently associated with advanced age (OR = 1.1, 95%CI 1.07–1.2), functional dependence (OR = 9.2, 95%CI 4.3–19.9), depression symptoms (OR = 3.8, 95%CI 1.6–9.2), risk of malnutrition or malnutrition (OR = 4.8, 95%CI 1.4–16.7) and having HbA1c ≥ 9.0% (OR = 2.4, 95%CI 1.08–5.3). Affected individuals exhibited poorer glycaemic control, higher complication rates, greater risk of malnutrition, and more frequent depressive symptoms compared with non-frail participants.

conclusionCognitive frailty among older adults with T2DM in rural Vietnam was associated with age, functional dependence, depression symptoms, risk of malnutrition or malnutrition and poor glycaemic control, highlighting the need for routine frailty screening and multidomain interventions. Incorporating simple, low-cost assessment tools into diabetes care at primary and provincial levels could enable early detection and tailored management for this vulnerable population.

Indexed as

Cognitive DysfunctionDiabetes Mellitus, Type 2Frail ElderlyFrailtyRural PopulationAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsVietnamCognitive frailtyFunctional dependenceOlder adultsRural healthType 2 diabetes mellitusVietnam

Identifiers

PMID41998534
PMCPMC13220445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.